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Wisconsin vs Iowa State Prediction, Bracketology and Pick for College Basketball NCAA Tournament

In a Round of 32 NCAA Tournament game, the (3) Wisconsin Badgers will face off with the (11) Iowa State Cyclones in the Midwest Region. Let’s take a look at the top college basketball betting odds, picks, bracketology, betting trends and KenPom Rankings, then give our Wisconsin vs Iowa State prediction for the game today. 

Wisconsin vs Iowa State | NCAA Tournament Bracketology

2022 NCAA Tournament
No. 3 Wisconsin Badgers (25-7) vs. No. 11 Iowa State Cyclones (21-12)
Date: Sunday, March 20, 2022
Time: 6:10 PM EST
Venue: Fiserv Forum — Milwaukee, WI
Coverage: TNT

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Wisconsin vs Iowa State College Basketball Betting Picks and Odds

All college basketball betting odds for Wisconsin vs Iowa State can be found at BetUS Sportsbook.

Moneyline: WISC: (-205) | ISU: (+175)
Point Spread: WISC: -5 (-105) | ISU: +5 (-115)
Total: 126 — Over: (-110) | Under: (-110)

KenPom Rankings | Bracketology

KenPom Rankings are from

Iowa State37104.889.766.0

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Iowa State vs Wisconsin Prediction, Bracketology and Pick for College Basketball NCAA Tournament
Credit: G Fiume/Getty Images
  • Iowa State is 5-3 against the spread (ATS) in its last eight games.
  • The UNDER is 3-1 in Iowa State’s last four games.
  • Wisconsin is 15-5 straight up in their last 20 games.
  • Wisconsin is 5-10 ATS in its last 15 games.
  • The UNDER is 4-1 in Wisconsin’s last five games.

Wisconsin vs Iowa State Prediction | March Madness Picks and Bracketology

In the First Round, Iowa State was able to outlast LSU in one of the ugliest games of the first round. The Cyclones won 59-54 in a game that saw both teams shoot under 38% from the field and 33% from deep. Iowa State was destroyed on the boards by LSU and will be in serious trouble if they let Wisconsin control the boards the same way.

It looked bleak for Wisconsin against Colgate when the Raiders hit six of seven three-pointers to start the second half. The defense adjusted well and was able to run them off the line. Johnny Davis improved his shot selection and the Badgers came back to win 67-60. With another “home” game for Wisconsin, the Badgers have a nice edge.

Both teams struggled on offense for stretches, but the total line is just too low. Both teams should see their offenses get back to their normal selves and easily score 60 points. Bet on the over to hit.

Our college basketball betting Wisconsin vs Iowa State prediction tonight will be Over HITS at BetUS

For what it’s worth, the ESPN Matchup Predictor gives Wisconsin a 59.2% chance to win.

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