In a March Madness Sweet 16 NCAA Tournament game, the 2-seed Duke Blue Devils will face off with the 3-seed Texas Tech Red Raiders in the West Region. Let’s take a look at the top college basketball betting odds, picks, bracketology, betting trends and KenPom Rankings, then give our Duke vs Texas Tech prediction for the game today. 

Duke vs Texas Tech | March Madness Sweet 16

2022 NCAA Tournament Sweet 16
No. 2 Duke Blue Devils (30-6) vs. No. 3 Texas Tech Red Raiders (27-9)
Date: Thursday, March 24, 2022
Time: 9:39 PM EST
Venue: Chase Center — San Francisco, CA
Coverage: CBS

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Duke vs Texas Tech College Basketball Betting Picks and Odds

All college basketball betting odds for Duke vs Texas Tech can be found at BetUS Sportsbook.

Moneyline: DUKE: (N/A) | TTU: (N/A)
Point Spread: DUKE: +1 (-110) | TTU: -1 (-110)
Total: 137.5 — Over: (-110) | Under: (-110)


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Credit: Rob Kinnan/USA TODAY

KenPom Rankings | Bracketology

KenPom Rankings are from KenPom.com

TeamRkAdjOAdjDAdjT
Duke9120.2 95.467.3
Texas Tech6110.2 84.4 66.5
  • Blue Devils are 6-0 ATS in their last six neutral site games as an underdog.
  • Seven of the Blue Devils’ last eight games have gone OVER the total.
  • The OVER is 6-0 in the Blue Devils’ last six games following a straight up win.
  • Red Raiders are 0-5 ATS in their last five games following a straight up win.
  • The total has gone UNDER in five of the Red Raiders’ last six NCAA Tournament games as a favorite.
  • Red Raiders are 14-3 ATS in their last 17 games against teams with a winning percentage above .600.

Duke vs Texas Tech Prediction | March Madness Sweet 16 Picks

Collectively, the Big 12 and ACC have been two of the most impressive conferences in the NCAA Tournament thus far. When it comes to the numbers and metrics that matter, Texas Tech ranks slightly ahead of Duke despite being wrongfully seeded under them in the West Region of the bracket.

Defense has been the calling card for Mark Adams’ Red Raiders all season long. Tech has surrendered all of 84.4 points per 100 possessions this season. This ranks as the No. 1 adjusted defensive efficiency in the country.

When it comes to Tech’s Sweet 16 matchup with Duke, that defensive prowess figures to be vital to slowing down the Blue Devils’ top-5 adjusted offense. Although a line move through pick’em is not necessarily the most significant, it is very noteworthy that the market flipped Texas Tech to the favorite in this game. Simply seeing Duke as a small college basketball picks underdog should raise the eyebrows of astute bettors.

Despite the program’s storied history and swaths of young talent on this Duke team, they will be hard-pressed to knock off one of the Big 12’s best squads. Outside of Paulo Banchero, the Blue Devils lack a true reliable scoring threat. This figures to be a massive problem against the best defense in all of college basketball. Led by Bryson Williams and Oral Roberts transfer Kevin Obanor, the Red Raiders have more experienced players as well.

Our college basketball betting Duke vs Texas Tech prediction tonight will be Texas Tech -1 at BetUS

For what it’s worth, the ESPN Matchup Predictor gives Texas Tech a 53.9% chance to win.


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Henry’s passion for sports dates all the way back to childhood and has ultimately led to a full-fledged career as an analyst and content creator. After getting his start penning fantasy football articles, he forrayed into the betting side of the business in early 2019. His love for sports and statistics proved to be an ideal match with the dedicated research and strategy that handicapping requires. Henry currently specializes in betting analysis and picks for college football, college basketball and NASCAR. He counts the NFL, the WNBA, and NBA player props as additional leagues/markets of interest. Henry graduated from SUNY Buffalo in 2021 with a Communication Studies degree and a Psychology minor. A native of the Finger Lakes region in Upstate New York, he and his pup, Harold, have since relocated to Laramie, Wyoming. Thanks to his professional goals within the sports betting industry, there has been a whole lot of steam on the odds for a move to Las Vegas in 2023! Most of Henry’s free time is spent on outdoor adventures, playing chess, snowboarding, or reading a good book. He is also a competitive powerlifter and aspires to qualify for the USAPL Nationals meet within the next 2-3 years.

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