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Rams vs Colts NFL Betting Odds, Trends, Stream and Picks for Week 2

After missing out on landing Matthew Stafford this offseason, the Indianapolis Colts will host him and the Los Angeles Rams in Week 2. The Rams showed off their offensive firepower last week, while the Colts barely made a spark. However, this NFL betting matchup could go either way in Week 2.

The following Rams vs Colts NFL betting preview will give you the current odds, betting trends and picks for the Week 2 matchup, along with a stream link to watch games all season long.

Rams vs Colts Week 2 NFL Betting Preview and Stream

NFL Regular Season — Week 2 Game
Los Angeles Rams (1-0, 0-0 Away) vs. Indianapolis Colts (0-1, 0-1 Home)
Date: Sunday, September 19, 2021
Time: 1:00 p.m. EST
Venue: Lucas Oil Stadium — Indianapolis, IN
Coverage: Click here for the stream

The Rams barely went into their playbook on Sunday Night Football, as they were in a completely different league than the Chicago Bears. Matthew Stafford is one step closer to proving all of his doubters wrong, and Sean McVay has to love it. There finally is a partnership there, instead of McVay babysitting Jared Goff in past seasons. Defensively, the Rams still have questions to be answered after some big offseason departures. However, this Rams offense looks good enough to carry the team during the weeks they need it.

As good as the Rams’ offense was, the opposite is true for the Colts. The offensive line was a wreck, but luckily Eric Fisher is ready to play this week. However, the Colts’ biggest issue all season long will be their lack of receiving weapons, especially with T.Y. Hilton out. Defensively, the Colts have playmakers at every level, but the offense needs to keep them off the field. It will be a tough NFL betting matchup again this week.

rams vs colts nfl betting trends picks odds
Credit: Julio Aguilar/Getty Images

Rams vs Colts Odds and Spread

NFL betting odds for Rams vs Colts are taken from FanDuel Sportsbook.

Moneyline: LAR: (-188) | IND: (+158)
Spread: LAR: -3.5 (-110) | IND: +3.5 (-110)
Total: 48.5 — Over: (-105) | Under: (-115)
Public (Spread) Betting Percentages via oddsFire: LAR: (48%) | IND: (52%)
Odds to Win Super Bowl LVI: LAR: (+1300) | IND: (+4000)

Rams vs Colts NFL Betting Trends

– The Rams are 1-0 against the spread (ATS) this season.
– The total hit the Over in the Rams’ first game this season.
– Indianapolis is 0-1 ATS this season.
– The total hit the Under in the Colts’ first game this season.

Rams vs Colts Stats

– The Rams are averaging 34.0 points per game (PPG) this season (No. 5 in the NFL).
– The Rams are surrendering 14.0 PPG this season (T-No. 5 in the NFL).
– Indianapolis is averaging 16.0 PPG this season (T-No. 25 in the NFL).
– Indianapolis is surrendering 28.0 PPG this season (No. 19 in the NFL).

Rams vs Colts Prediction

The Rams vs Colts NFL betting prediction uses the NumberFire Picks tool.

Rams -4: 38.8%
Colts +4: 58.4%
Push: 2.8%


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