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Duke vs North Carolina Prediction, Odds and Start Time for March Madness Final Four

In the second March Madness Final Four NCAA Tournament game of the evening, the West Region champion Duke Blue Devils will face off with a familiar foe in the North Carolina Tar Heels. Surprisingly, this is the first Duke vs UNC matchup we have seen in the NCAA Tournament! Let’s take a look at the top college basketball betting odds, picks, bracketology, betting trends and KenPom Rankings, then give our Duke vs North Carolina prediction for the game Saturday. 

Duke vs North Carolina | March Madness Final Four

2022 NCAA TournamentFinal Four
No. 2 Duke Blue Devils (32-6) vs. No. 8 North Carolina Tar Heels (28-9)
Date: Saturday, April 2, 2022
Time: 8:49 PM EST
Venue: Caesars Superdome — New Orleans, LA
Coverage: TBS


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Duke vs North Carolina College Basketball Betting Picks and Odds

All college basketball betting odds for Duke vs North Carolina can be found at BetUS Sportsbook.

Moneyline: DUKE: (-190) | UNC: (+165)
Point Spread: DUKE: -4 (-110) | UNC: -4 (-110)
Total: 151 — Over: (-110) | Under: (-110)


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Duke vs North Carolina Prediction, Odds and Time for March Madness Final Four
Credit: Rob Kinnan/USA TODAY

KenPom Rankings | Bracketology

KenPom Rankings are from KenPom.com

TeamRkAdjOAdjDAdjT
Duke9120.295.467.3
North Carolina20113.995.470.5
  • The OVER is 6-0 in their last six Duke vs North Carolina matchups.
  • Duke is 13-2 straight up in their last 15 games.
  • The OVER is 8-2 in Duke’s last 10 games.
  • North Carolina is 8-1 against the spread (ATS) in their last nine games.
  • The Tar Heels are 8-2 ATS in their last 10 matchups against Duke.
  • North Carolina is 10-1 straight up in their last 11 games.

Duke vs North Carolina Prediction | March Madness Final Four Picks

The road to the Final Four for Duke hasn’t been through many tough opponents. They haven’t gone up against a great offense, which is exactly what North Carolina has. Duke saw this in their last meeting, with the Tar Heels putting up 94 points.

UNC has been solid in the NCAA Tournament as well. They have scored over 90 points in each of the first two rounds. North Carolina has also fought through some defensive-minded opponents while still scoring well. With Duke ranking only 45th in defensive efficiency, we should see plenty of points.

Instead of picking a winner, we will go with the trends and pick this game to hit the OVER.

Our college basketball betting Duke vs North Carolina prediction tonight will be OVER 151 at BetUS

For what it’s worth, the ESPN Matchup Predictor gives Duke a 68.4% chance to win.


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