In Game 3 of a four-game series in the NL Central, the St. Louis Cardinals are taking on the Milwaukee Brewers. Yesterday, the Cardinals picked up the 6-2 road win. The MLB oddsmakers’ Cardinals vs Brewers prediction for today sides with the home team, but will they be able to bounce back from yesterday’s loss?

Let’s take a closer look at this MLB game today in Milwaukee, looking at the top MLB betting odds, trends and starting pitchers today. But first, let’s take a look at this special welcome offer from BetOnline Sportsbook.

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Cardinals vs Brewers Prediction and MLB Betting Preview

MLB Regular Season Game
St. Louis Cardinals (39-31, 18-18 Away) vs. Milwaukee Brewers (39-31, 16-13 Home)
Date: Wednesday, June 22, 2022
Start Time: 8:10 p.m. EST
Venue: American Family Field — Milwaukee, WI

Credit: Benny Sieu/USA TODAY Sports

Cardinals vs Brewers Starting Pitchers

Cardinals: Adam Wainwright (5-5 Record, 3.06 ERA)
Brewers: Eric Lauer (6-2 Record, 3.57 ERA)

Cardinals vs Brewers MLB Betting Odds

MLB betting odds for Cardinals vs Brewers are taken from BetOnline Sportsbook.

Moneyline: STL: (-126) | MIL: (+116)
Run Line: STL: -1.5 (+120) | MIL: +1.5 (-140)
Total: 9 — Over: (-120) | Under: (+100)
Public Betting Percentages via Action Network: STL: (28%) | MIL: (72%)

  • Yesterday, the Cardinals defeated the Brewers, 6-2.
  • The Cardinals are 2-4 straight up in their last six games.
  • The OVER is 8-3 in the Cardinals’ last 11 games.
  • The Cardinals are 2-6 straight up in their last eight road games.
  • The Brewers are 4-1 straight up in their last five games.
  • The UNDER is 4-1 in Milwaukee’s last five games against the NL Central.
  • The Brewers are 1-7 straight up in their last eight home games.

Cardinals vs Brewers Stats

  • St. Louis is averaging 4.81 runs per game (RPG) this season (T-No. 5 in the MLB).
  • St. Louis is surrendering 3.91 RPG this season (No. 6 in the MLB).
  • Milwaukee is averaging 4.33 RPG this season (No. 16 in the MLB).
  • Milwaukee is surrendering 4.13 RPG this season (T-No. 12 in the MLB).

Cardinals vs Brewers Prediction | MLB Betting Picks

This Cardinals vs Brewers prediction is made through the ESPN Matchup Predictor. According to the tool, the St. Louis Cardinals have a 51.1% chance to win today.


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I am a simple Wisconsin man: I love beer and sports. I decided to create FlurrySports because I was sick of the politics and non-stories that the fat cat corporations put out. When you see football articles from me, just know that I combine my knowledge from playing, coaching, athletic training, and sports management/economic courses to give you a unique, but I feel well-rounded point of view. I am always down to talk about anything, so follow me on Twitter @FantasyFlurry if you decide you want more of me!

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