When it comes to successful DraftKings NFL DFS picks, using the top QB-WR stacks on a given slate can be very beneficial for the potential success of your lineup. For example, every time your top quarterback completes a pass to his top wide receiver, and you stacked those two in your DFS lineup –– BOOM! You’re getting double the fantasy football value! 

So, let’s dive into Week 10 of the NFL season and discuss which QB-WR stacks and DraftKings NFL DFS picks are worth rostering for this week’s Fantasy Football Millionaire DFS contest. Keep in mind that players from MIA, PHI, KC and LAR are on their bye and will be missing from this week’s slate. 

To enter the contest and create your own DFS lineups, click here.

Best DraftKings NFL DFS Stacks at QB-WR for Week 10

Jared Goff ($6,400) and Amon-Ra St. Brown ($8,300) vs. Chargers | NFL DFS Picks

While Jared Goff struggled to put together a solid fantasy outing in Weeks 7 and 8 after posting back-to-back 25-plus DKFP performances, he’s still looking Amon-Ra St. Brown‘s way often –– making them one of the top DFS stacks of the week. The Lions are coming off a bye and will be well-rested to take advantage of a Chargers’ defense that ranks 23rd in defensive DVOA (5.2%) and allows the most passing yards per game (286.0) this season. On top of that, their secondary has allowed the 10th-most fantasy points to opposing wide receivers (312.2). 

I’m not expecting a shootout because the Lions’ pass rush and effective run defense should give the Chargers issues but it’s a difficult task to slow down Justin Herbert and company. The game script should be even and if Los Angeles comes out swinging, maybe we can get another 15-plus target game from St. Brown again, making him and Goff one of the best DraftKings NFL DFS stacks for Week 10. 


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Trevor Lawrence ($6,000) and Christian Kirk ($6,000) vs. 49ers | NFL DFS Picks

Just like the Lions, the Jaguars are coming off a bye and will be well-prepared to take advantage of a 49ers’ team that has lost three straight games and has surrendered the seventh-most passing yards per game (272.7) in that span. However, the 49ers are going to come out with intensity and try to dominate this game, making it a good spot for Trevor Lawrence and Christian Kirk to exploit their defensive weaknesses all game with an even game script. 

Lawrence has yet to post more than 21 DKFP in a single game this season and that likely won’t change against San Francisco’s pass rush but he’s attempted 30 passes in all but one game. Kirk has slowly usurped the WR1 role over Calvin Ridley ($5,600) at this point as he’s gone over 13.9 DKFP in six of eight games and has caught a touchdown in two of his last three games this season. Assuming San Fran is back to its normal ways, Lawrence will be depended on and hopefully give us a season-high performance in the process. 

Will Levis ($5,300) and DeAndre Hopkins ($6,000) vs. Buccaneers | NFL DFS Picks

Let’s get risky with the NFL DFS value play for this week and roster Will Levis and DeAndre Hopkins against the Buccaneers, who just let rookie CJ Stroud throw for over 470 yards and five touchdowns in Week 9. Titans HC Mike Vrabel committed to Levis as the starter this week but his sample size is still just two games, so it’s hard what to make of him. He surely makes the Titans’ pass-catchers fantasy value higher, which is what matters here and especially with Hopkins. Hopkins has been targeted 17 times in Levis’ two starts and is so obviously his safety blanket in crucial downs. Hopkins only posted 10.5 DKFP last week as the duo’s connection soured in the second half but the willingness to get him the ball down the field is apparent. 

We can’t expect Hopkins to haul in three touchdowns every week but he certainly has a good chance to find the endzone against Tampa Bay, who has allowed the second-most passing yards per game (279.4) and third-most receiving touchdowns to opposing wide receivers (10) this season. Levis had a strong debut followed by a mediocre performance against a stout defense… can he bounce back? I think so and in a big way. 


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