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LSU vs Iowa State Prediction, Bracketology and Pick for College Basketball NCAA Tournament

In a First Round NCAA Tournament game, the (6) LSU Tigers will face off with the (11) Iowa State Cyclones in the Midwest Region. Let’s take a look at the top college basketball betting odds, picks, bracketology, betting trends and KenPom Rankings, then give our LSU vs Iowa State prediction for the game today. 

LSU vs Iowa State | NCAA Tournament Bracketology

2022 NCAA Tournament
No. 6 LSU Tigers (22-11) vs. No. 11 Iowa State Cyclones (20-12)
Date: Friday, March 18, 2022
Time: 7:20 PM EST
Venue: Fiserv Forum — Milwaukee, WI
Coverage: TBS

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LSU vs Iowa State College Basketball Betting Picks and Odds

All college basketball betting odds for LSU vs Iowa State can be found at BetUS Sportsbook.

MoneyLine: LSU: (-185) | ISU: (+165)
Point Spread: LSU: -4 (-110) | ISU: +4 (-110)
Total: 127 — Over: (-110) | Under: (-110)

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LSU vs Iowa State Prediction, Bracketology and Pick for College Basketball NCAA Tournament
Credit: Charlie Neibergall/AP Photo

KenPom Rankings | Bracketology

KenPom Rankings are from

Iowa State48104.490.466.1
  • LSU is 5-10 against the spread (ATS) in its last 15 games.
  • The OVER is 11-3 in LSU’s last 14 games.
  • LSU is 1-5 straight up against their last six Big 12 opponents.
  • Iowa State is 5-1 ATS against their last six SEC opponents.
  • The OVER is 6-3 in Iowa State’s last nine games.
  • Iowa State is 0-10 straight up in its last 10 March games.

LSU vs Iowa State Prediction | March Madness Picks and Bracketology

This is an interesting matchup that could turn sloppy. LSU has a strong defense and is the top team in the nation in forcing steals. However, they have a problem with turning the ball over. On the other side, Iowa State is super inconsistent, but they also generate turnovers well.

Of course, LSU will be playing under a new head coach in the NCAA Tournament, with Will Wade getting fired. This feels like one of those situations that bring a team together. I’ll go with them to win the game, but it could be a one-possession game.

For the best bet, we’ll side with the betting trends and take the over. Both schools have consistently had point totals go over.

Our college basketball betting LSU vs Iowa State prediction tonight will be the point total going OVER at BetUS

For what it’s worth, the ESPN Matchup Predictor gives TCU a 50.3% chance to win.

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