Betting

Jaguars vs Colts NFL Odds, NFL Picks, Props, and Betting Trends

Published by
Henry John

Two teams with polar opposite records are set to face off in Week 17 action when the Jacksonville Jaguars take on the Indianapolis Colts. The Jaguars have already accomplished their primary goal this season which was securing the number one overall pick in the 2021 NFL Draft. The Colts can get one step closer to accomplishing theirs with a win on Sunday as they battle for an AFC playoff spot. As one might expect, the NFL odds and NFL picks heavily favor the home team in this one.

This betting preview contains the NFL odds, key betting trends, prop bets, and best NFL picks for Jaguars vs Colts on Sunday afternoon.


Check out our Week 17 NFL Survivor Picks!


NFL Odds, NFL Picks, and NFL Props | Jaguars vs Colts

Jaguars vs Colts Game Info

Jacksonville Jaguars (1-15, 0-7 Away) at Indianapolis Colts (10-5, 5-2 Home)
Date: Sunday, Jan. 3, 2020
Time: 4:25 p.m. EST
Venue: Lucas Oil Stadium – Indianapolis, IN
Coverage: CBS
Attendance: About 10,000 fans will be allowed to attend.

Photo by Julio Aguilar/Getty Images

Jaguars vs Colts NFL Odds + NFL Picks

Opening Lines: Colts -13.5; O/U 49.5
Moneyline: JAX: (+750) | IND: (-1200)
Spread: JAX: +14 (-115) | IND: -14 (-105)
Total: 49.5 — Over: (-110) | Under: (-110)

All odds courtesy of MyBookie Sportsbook

Jaguars vs Colts Overview

Given the trajectory that these two teams have followed this season, it seems pretty hard to believe that it was the Jaguars who won their Week 1 matchup as sizable NFL picks underdogs. That game seems like ages ago, and it’s worth noting that Jacksonville was outplayed in most statistical categories even as they emerged victoriously. Having not won since, the Jags have secured the draft rights to highly touted quarterback prospect Trevor Lawrence. With the number one pick already clinched, it is worth noting that the Jaguars have no incentive to lose this week. Can Mike Glennon do in Week 17 just as Gardner Minshew did in Week 1 and spoil the Colts’ postseason aspirations?

Even as the Colts have piled up ten NFL picks wins this season, it’s worth noting that none have necessarily come in a dominant fashion. After getting up big on Pittsburgh last week, Indianapolis’ offense sputtered in the second half, and the Colts now need a win plus help in Week 17 to reach the playoffs. Philip Rivers amassed over 360 yards passing the first time the teams played this year, but his two interceptions proved quite costly. With the Colts running game rounding into form over the back half of the season, look for Frank Reich’s game plan to involve a heavy dose of Jonathan Taylor as the Colts try to wear down the Jacksonville defensive front.

Jaguars vs Colts Betting Trends

  • Jaguars 2020 Betting Trends: 6-9 ATS; 8-7 to the Over
  • Colts 2020 Betting Trends: 8-7 ATS; 9-6 to the Over
  • The Jaguars are 3-1 straight up and ATS in their last four head-to-head meetings against the Colts.
  • Home teams have won outright in each of the last six and in ten of the last 12 head-to-head meetings between the Jaguars and Colts.
  • Four of the last five head-to-head meetings between the Jaguars and Colts have gone Over the total.

Jaguars vs Colts Stats

  • Jacksonville has averaged 19.5 points per game (PPG) this season (Tied for No. 29 in the NFL)
  • Jacksonville has surrendered 30.9 PPG this season (No. 31 in the NFL)
  • Indianapolis has averaged 28.2 PPG this season (No. 9 in the NFL)
  • Indianapolis has surrendered 23.2 PPG this season (Tied for No. 12 in the NFL)

Monkey Knife Fight NFL Props

Monkey Knife Fight is a DFS site unlike DraftKings or FanDuel. Instead, the contests feature props to play, with varying multipliers for each contest. Unlike the aforementioned sites, you are only competing with yourself when making NFL picks on MKF, and you do not need to worry about annoying salary caps.

Related Post

Monkey Knife Fight has several great NFL props for the entire Week 17 slate. Here is one that I like for the Jaguars vs Colts game.

This NFL picks prop at Monkey Knife Fight only requires us to pick two of the three fantasy points matchups correctly to win. While Philip Rivers clearly has the better matchup of the two quarterbacks, I’m not convinced that he will dwarf Mike Glennon in fantasy points. I’ll take the Jaguars signal-caller catching 5.5 points.

While I expect both Jonathan Taylor and T.Y. Hilton to have solid games as two of the Colts’ biggest offensive weapons, it’s hard to beat the volume that Taylor gets on a weekly basis. Finally, I’ll elect to roll with Jacksonville running back Dare Ogunbowale to finish with more fantasy points than Nyheim Hines. We’ve seen all year what James Robinson has done as the primary Jaguars RB. Ogunbowale’s pass-catching abilities serve him well in NFL picks that focus on fantasy football stats.

Picking two of the three matchups correctly would win you 1.5x your buy-in.

CLICK HERE and use the promo code FLURRY to get a 100% deposit match up to $50!

Jaguars vs Colts NFL Picks and NFL Odds

The NFL picks spread has inched upward in favor of the sizable home favorite Colts throughout the week leading up to this AFC South showdown. Bettors now must lay a full 14 points with Indianapolis at the vast majority of shops. While the Colts have far more incentive to win and are clearly the better team on paper, that sure is a hefty number.

I don’t see any play here other than taking the two full touchdowns with the Jaguars. We saw Jacksonville spring the Week 1 upset with an outright win as seven-point NFL picks underdogs at home. Yes, that final score was a fluke considering the box score. Yes, the Jags haven’t won a game sense. Yes, the Colts need to win this game to have a shot at the postseason. In the end, none of the narratives surrounding this “lopsided” matchup are enough to warrant a two-touchdown spread. Jacksonville has no pressure whatsoever in Week 17, and that just might be a good thing.

Pick: Jaguars +14 (-115 at MyBookie Sportsbook)

This post was last modified on January 2, 2021 1:42 PM

Henry John

Henry John is a multi-sport analyst specializing in motorsports, football, and betting markets. His work focuses on performance trends, strategy, and data-driven insights to better understand outcomes and identify value. With experience producing content across multiple platforms, Henry has written extensively on NASCAR, college football, the NFL, and other major sports, developing structured analysis that goes beyond surface-level recaps. His approach blends statistical evaluation, betting market awareness, and game-level context to break down how and why results happen. Outside of sports, Henry enjoys strength training, outdoor activities, and continuous learning in analytics and performance.

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