In the final game of a three-game series in the AL Central, the Cleveland Guardians are taking on the Minnesota Twins. Yesterday, Guardians won a high-scoring matchup, 11-10. The MLB oddsmakers’ Guardians vs Twins prediction for today sides with the home team.

Let’s take a closer look at this MLB game today in Minnesota, looking at the top MLB betting odds, trends and starting pitchers today. But first, let’s take a look at this special welcome offer from BetOnline Sportsbook.

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Guardians vs Twins Prediction and MLB Betting Preview

MLB Regular Season Game
Cleveland Guardians (36-28, 20-18 Away) vs. Minnesota Twins (38-32, 20-16 Home)
Date: Thursday, June 23, 2022
Start Time: 1:10 p.m. EST
Venue: Target Field — Minneapolis, MN

Credit: Allan Henry/USA TODAY Sports

Guardians vs Twins Starting Pitchers

Guardians: Zach Plesac (2-4 Record, 4.41 ERA)
Twins: Devin Smeltzer (3-1 Record, 3.52 ERA)

Guardians vs Twins MLB Betting Odds

MLB betting odds for Guardians vs Twins are taken from BetOnline Sportsbook.

Moneyline: CLE: (+121) | MIN: (-131)
Run Line: CLE: +1.5 (-165) | MIN: -1.5 (+145)
Total: 9.5 — Over: (-115) | Under: (-105)
Public Betting Percentages via Action Network: CLE: (61%) | MIN: (39%)

  • Yesterday, the Guardians defeated the Twins, 11-10.
  • The Guardians are 8-1 straight up in their last nine games.
  • The OVER is 5-1 in Cleveland’s last six games against the American League.
  • The Guardians 5-1 straight up in their last six road games.
  • The OVER is 5-2 in the last seven Guardians vs Twins matchups.
  • The Twins are 13-7 in their last 20 home games against the Guardians.
  • The OVER is 9-2 in Minnesota’s last 11 home games.

Guardians vs Twins Stats

  • Cleveland is averaging 4.69 runs per game (RPG) this season (No. 10 in the MLB).
  • Cleveland is surrendering 4.11 RPG this season (No. 11 in the MLB).
  • Minnesota is averaging 4.50 RPG this season (No. 14 in the MLB).
  • Minnesota is surrendering 4.17 RPG this season (No. 14 in the MLB).

Guardians vs Twins Prediction | MLB Betting Picks

This Guardians vs Twins prediction is made through the ESPN Matchup Predictor. According to the tool, the Minnesota Twins have a 63.5% chance to win today.


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I am a simple Wisconsin man: I love beer and sports. I decided to create FlurrySports because I was sick of the politics and non-stories that the fat cat corporations put out. When you see football articles from me, just know that I combine my knowledge from playing, coaching, athletic training, and sports management/economic courses to give you a unique, but I feel well-rounded point of view. I am always down to talk about anything, so follow me on Twitter @FantasyFlurry if you decide you want more of me!

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