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Duke vs Syracuse Prediction and College Basketball Betting Picks

In an ACC college basketball matchup today, the Duke Blue Devils are taking on the Syracuse Orange at Carrier Dome. Let’s take a look at the top college basketball betting odds, picks, betting trends and KenPom Rankings, then give our Duke vs Syracuse prediction for the game today. 

Duke vs Syracuse Game Info

Duke Blue Devils (24-4, 14-3 ACC) vs. Syracuse Orange (15-13, 9-8 ACC)
Date: Saturday, February 26, 2022
Time: 6 PM EST
Venue: Carrier Dome — Syracuse, NY
Coverage: ESPN

Duke vs Syracuse College Basketball Betting Picks and Odds

All college basketball betting odds for Duke vs Syracuse can be found at BetUS Sportsbook.

Moneyline: DUKE: (-320) | SYRA: (+260)
Point Spread: DUKE: -7.5 (-110) | SYRA: +7.5 (-110)
Total: 151.5 — Over: (-110) | Under: (-110)

Duke vs Syracuse Prediction and College Basketball Betting Picks
Credit: Rob Kinnan/USA TODAY Sports

KenPom Rankings

KenPom Rankings are from KenPom.com

TeamRkAdjOAdjDAdjT
Duke9118.293.368.1
Syracuse80115.0104.768.4
  • Duke is 2-4 against the spread in their last six games.
  • The Blue Devils are 6-0 straight up in their last six road games.
  • Duke is 4-1 ATS in their last five games against Syracuse.
  • Syracuse is 6-2 straight up in their last eight games.
  • The total has hit the OVER in five of Syracuse’s last seven games against Duke.
  • Syracuse is 5-0 straight up in their last five home games.

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Duke vs Syracuse Prediction | College Basketball Betting Picks

The ACC is not very strong this season, but Duke is clearly the cream of the crop. They have just one loss in their last 11 games, which was a one-point game against Virginia. Duke beat Syracuse during this span, winning by 20 points at home. It was a balanced approach from the Blue Devils, with four starters scoring exactly 15 points each.

While Syracuse isn’t a bad team, they are a couple of tiers below Duke. Coach K also isn’t going to lose what could possibly be his final game against Jim Boeheim. This should be a double-digit spread. Since it’s not, we’ll take Duke to cover on the road.

Our college basketball betting Duke vs Syracuse prediction tonight will be Duke COVERS at BetUS

For what it’s worth, the ESPN Matchup Predictor gives Duke a 75.1% chance to win.

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