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Bills vs Titans NFL Betting Odds, Trends, Picks and Stream for MNF Week 6

To cap off this exciting NFL Week 6, we have an AFC showdown on Monday Night Football, with the Buffalo Bills taking on the Tennessee Titans. With both teams being the NFL betting favorites to win their divisions, the result of this matchup could have seeding implications down the road.

The following Bills vs Titans NFL betting preview will give you the current odds, betting trends and picks for the Week 6 matchup, along with a stream link to watch games all season long.

Bills vs Titans MNF Week 6 NFL Betting Preview and Stream

NFL Regular Season — Week 6 Monday Night Football
Buffalo Bills (4-1, 2-0 Away) vs. Tennessee Titans (3-2, 1-1 Home)
Monday, October 18, 2021
 8:15 p.m. EST
 Nissan Stadium — Nashville, TN
Coverage: Click here for the stream

Following their Week 1 loss, it has been absolute dominance for the Bills. They have outscored their opponents 156-41 over the past four weeks. The defense is playing well and Buffalo has found a competent running game — two things the team was missing last season. This looks to be the most complete team in the NFL, and Tennessee will need to play their best game, especially defensively, to win this game on Monday Night Football.

The Titans continue to get healthier on the offensive side of the ball. The receiving corps looks complete yet again, with A.J. Brown and Julio Jones both starting at wide receiver. While that receiving duo should be feared, this team’s identity will still be pounding the rock with Derrick Henry, who has averaged nearly 150 rushing yards the past four games. Defensively, however, this team is bad. They allow 6.2 yards per play, which is tied for the fifth-worst in the league.

nfl betting trends odds stream picks bills vs titans
Credit: Getty Images

Bills vs Titans Odds & Spread

NFL betting odds for Bills vs Titans are taken from BetMGM Sportsbook.

Moneyline: BUF: (-250) | TEN: (+210)
 BUF: -6 (-110) | TEN: +6 (-110)
Total: 53.5 — Over: (-115) | Under: (-105)
Public (Spread) Betting via Action Network:  BUF: (89%) | TEN: (11%)
Odds to Win Super Bowl LVI: BUF: (+550) | TEN: (+2800)

Bills vs Titans NFL Betting Trends

– Buffalo is 2-3 against the spread (ATS) this season.
– The Over is 1-4 for the Bills this season.
– Tennessee is 2-3 ATS this season.
– The Over is 1-4 for the Titans this season.

Bills vs Titans Stats

– Buffalo is averaging 34.4 points per game (PPG) this season (No. 1 in the NFL).
– Buffalo is surrendering 12.8 PPG this season (No. 1 in the NFL).
– Tennessee is averaging 26.4 PPG this season (No. 8 in the NFL).
– Tennessee is surrendering 26.0 PPG this season (No. 24 in the NFL).

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Bills vs Titans Prediction

The Bills vs Titans NFL betting prediction uses the ESPN Football Power Index.

Bills: 71.6%
Titans: 28.1%
Tie: 0.2%

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