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Wyoming vs Indiana Prediction, KenPom Rankings and Picks for NCAA Tournament First Four

In an NCAA Tournament First Four game, the Wyoming Cowboys will take on the Indiana Hoosiers for a spot in the big dance! The winner of this matchup will face Saint Mary’s in the First Round. Let’s take a look at the top college basketball betting odds, picks, bracketology, betting trends and KenPom Rankings, then give our Wyoming vs Indiana prediction for the game today. 

Wyoming vs Indiana | NCAA Tournament Bracketology

2022 NCAA Tournament — First Four Game
Wyoming Cowboys (25-8) vs. Indiana Hoosiers (20-13)
Date: Tuesday, March 15, 2022
Time: 9:10 PM EST
Venue: UD Arena — Dayton, OH
Coverage: TRUTV

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Wyoming vs Indiana College Basketball Betting Picks and Odds

All college basketball betting odds for Wyoming vs Indiana can be found at BetUS Sportsbook.

Moneyline: WYO: (+155) | IU: (-175)
Point Spread: WYO: +4 (-110) | IU: -4 (-110)
Total: 132.5 — Over: (-110) | Under: (-110)


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Wyoming vs Indiana Prediction, KenPom Rankings and Picks for NCAA Tournament First Four
Credit: Trevor Ruszkowski / USA Today Sports

KenPom Rankings | Bracketology

KenPom Rankings are from KenPom.com

TeamRkAdjOAdjDAdjT
Wyoming58110.297.166.0
Indiana36107.692.667.0
  • Wyoming are 2-3 against the spread (ATS) in their last five games.
  • The UNDER is 3-2 in Wyoming’s last five games.
  • Wyoming are 2-2 straight up in their last five games.
  • Indiana are 3-2 ATS in their last five games.
  • The OVER is 3-2 in Indiana’s last five games.
  • Indiana are 4-8 ATS in their last 12 road games.

Wyoming vs Indiana Prediction | March Madness Picks and Bracketology

Wyoming struggled to end the season and they are a two-man show. Overall, Indiana is a better team, but they have a tendency to go ice-cold from downtown.

For me, the difference in this game is Indiana big man Trayce Jackson-Davis. He is a solid scorer and talented interior defender, which will be the difference. With Mike Woodson as the head coach, Indiana could also potentially be dangerous in March. Woodson will likely be a better tournament coach, keeping his team’s focus in the right place and getting results.

Our college basketball betting Wyoming vs Indiana prediction tonight will be Indiana covering the spread at BetUS

For what it’s worth, the ESPN Matchup Predictor gives Indiana an 80% chance to win.


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