In what is expected to be the most lopsided game of NFL Week 5, the Pittsburgh Steelers will take on the Buffalo Bills. Rookie Kenny Pickett will be making his first NFL start in this Steelers vs Bills game.
This NFL betting preview will discuss our Steelers vs Bills prediction, NFL betting trends, odds and Week 5 NFL picks against the spread. But first, let’s take a look at this exciting NFL betting signup offer at BetOnline Sportsbook.
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Steelers vs Bills Prediction | Week 5 NFL Picks Against the Spread
NFL Regular Season — Week 5
Pittsburgh Steelers (1-3, 1-1 Away) vs. Buffalo Bills (3-1, 1-0 Home)
Date: Sunday, Oct. 9, 2022
Time: 1 PM EST
Venue: Highmark Stadium — Orchard Park, NY
Coverage: CBS
Steelers vs Bills Prediction, NFL Picks Against the Spread and Betting Odds
NFL betting odds for Steelers vs Bills are taken from BetOnline Sportsbook.
Moneyline: PIT: (+640) | BUF: (-900)
Spread: PIT: +14 (-110) | BUF: -14 (-110)
Total: 46 — Over: (-110) | Under: (-110)
Public (Spread) Betting via Action Network: PIT: (62%) | BUF: (38%)
Steelers vs Bills NFL Betting Trends
- The Steelers are 1-2-1 in NFL picks against the spread (ATS) this season.
- The OVER is 2-2 in Pittsburgh’s games this season.
- The Bills are 2-1-1 in NFL picks ATS this season.
- The OVER is 1-3 in Buffalo’s games this season.
Steelers vs Bills Stats
- Pittsburgh averages 18.5 points per game (PPG) this season (T-No. 23 in the NFL).
- Pittsburgh surrenders 22.5 PPG this season (No. 15 in the NFL).
- Buffalo averages 28.5 PPG this season (No. 5 in the NFL).
- Buffalo surrenders 14.5 PPG this season (No. 2 in the NFL).
Steelers vs Bills Prediction
This Week 5 NFL betting Steelers vs Bills prediction uses NumberFire’s game projections. They give Buffalo an 84.3% chance to win this Week 5 matchup.
The FlurrySports experts also have their own Week 5 NFL Picks here.
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