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Rams vs 49ers NFL Betting Odds, Trends, Picks and Stream for MNF Week 10

We have an NFC West showdown on Monday Night Football, with the Los Angeles Rams taking on the San Francisco 49ers. Both teams will be looking to get back into the win column, after both suffered losses last week, but which team will prevail? The following Rams vs 49ers NFL betting preview will give you the current odds, betting trends and picks for the Week 10 matchup, along with a stream link to watch games all season long.

Rams vs 49ers MNF Week 10 NFL Betting Preview

NFL Regular Season — Week 10 Monday Night Football
Los Angeles Rams (7-2, 4-0 Away) vs. San Francisco 49ers (3-5, 0-4 Home)
Date: Monday, November 15, 2021
Time: 8:15 p.m. EST
Venue: Levi’s Stadium — Santa Clara, CA
Coverage: Click here for the stream

The Rams have had an interesting couple of weeks. First, they traded for Von Miller to make their defensive line incredibly scary. He ended up not playing in the game, and they got crushed by the Titans. Then, the Rams won the Odell Beckham Jr. sweepstakes only to have their WR2, Robert Woods, tear his ACL the following day. They still look like one of the best teams in the NFL this season, and that’s clearly what they are hoping for. They have pushed all of their chips to the center, making this season “Super Bowl or bust.”

The 49ers, on the other hand, are looking like they are about to have their fourth losing season of the Kyle Shanahan era, with his lone winning season being the year he went to the Super Bowl. Shanahan wanted his team to draft Mac Jones, not Trey Lance, and he is acting like it this entire season. The defense no longer scares anyone, the offense lacks creativity and Jimmy Garoppolo is clearly not good enough to overcome these other obstacles. This does feel like a game they could win to mess with everyone, but they are not a good football team.

rams vs 49ers prediction nfl betting trends picks odds
Credit: Mike Dinovo-USA TODAY Sports

Rams vs 49ers Odds & Spread

NFL betting odds for Rams vs 49ers are taken from BetMGM Sportsbook.

Moneyline: LAR: (-200) | SF: (+168)
Spread: LAR: -3.5 (-110) | SF: +3.5 (-110)
Total: 50.5 — Over: (-108) | Under: (-112)
Public (Spread) Betting via Action Network: LAR: (75%) | SF: (25%)
Odds to Win Super Bowl LVI: LAR: (+750) | SF: (+12000)

Rams vs 49ers NFL Betting Trends

– Los Angeles is 4-5 against the spread (ATS) this season.
– The Over is 5-3-1 for the Rams this season.
– San Francisco is 2-6 ATS this season.
– The Over is 5-3 for the 49ers this season.

Rams vs 49ers Stats

– The Rams are averaging 29.0 points per game (PPG) this season (No. 4 in the NFL).
– The Rams are surrendering 21.8 PPG this season (No. 11 in the NFL).
– San Francisco is averaging 23.1 PPG this season (T-No. 17 in the NFL).
– San Francisco is surrendering 25.2 PPG this season (No. 24 in the NFL).


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Rams vs 49ers Prediction

The Rams vs 49ers NFL betting prediction uses the ESPN Football Power Index.

Rams: 60.0%
49ers: 39.7%
Tie: 0.3%

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