After a wild NFL Sunday, which even featured Dan Campbell getting his first win with the Lions, we wrap this week up with a big divisional matchup on Monday Night Football. The New England Patriots and Buffalo Bills will face off in what appears to be an extremely important matchup for divisional standings one month from now. It’s a close one in the NFL betting odds, so anything could happen tonight.

The following Patriots vs Bills NFL betting preview will give you the current odds, betting trends and picks for the Week 13 matchup, along with a stream link to watch games all season long.

Patriots vs Bills MNF Week 13 NFL Betting Preview and Stream

NFL Regular Season — Week 13 Game
New England Patriots (8-4, 5-0 Away) vs. Buffalo Bills (7-4, 3-2 Home)
Date: 
Monday, December 6, 2021
Time: 8:15 p.m. EST
Venue: Highmark Stadium — Orchard Park, NY
Coverage: Click here for the stream

This is a massive game atop the AFC East. The winner will take over the top spot in the division, though there will be another matchup between these teams in Week 16.

The Patriots have the longest winning streak in the NFL, winning six games in a row. A strong special teams unit kept them in games last season. That unit remains strong this year, but they add to that an elite defense and an efficient offense. While some want to criticize Mac Jones for being a “game manager” as if it is an insult, the Patriots can point to a couple of decades of greatness with their system sporting a game manager under center.

You can’t help but to think this is a must-win game for the Bills. Having the road to the Super Bowl go through Buffalo would be a big advantage, and it will be tough to win at New England in a couple of weeks. While they have won three of their past five games, the wins have come against the Saints, Jets and Dolphins. Josh Allen has taken noticeable steps forward in each of his first three seasons in the NFL, but there seems to be a noticeable step backward this season. He needs to be better for the Bills to get over the hump as a franchise.

Credit: Tim Heitman/USA TODAY Sports

Patriots vs Bills Odds & Spread

NFL betting odds for Patriots vs Bills are taken from BetMGM Sportsbook.

Moneyline: NE: (+120) | BUF: (-145)
Spread: NE: +3 (-115) | BUF: -3 (-105)
Total: 40.5 — Over: (-110) | Under: (-110)
Public (Spread) Betting via Action Network: NE: (81%) | BUF: (19%)
Odds to Win Super Bowl LVI: NE: (+1100) | BUF: (+800)

Patriots vs Bills NFL Betting Trends

– New England is 8-4 against the spread (ATS) this season.
– The Over is 6-6 for the Patriots season.
– Buffalo is 6-4-1 ATS this season.
– The Over is 5-6 for the Bills this season.

Patriots vs Bills Stats

– New England is averaging 28.0 points per game (PPG) this season (T-No. 6 in the NFL).
– New England is surrendering 15.8 PPG this season (No. 1 in the NFL).
– Buffalo is averaging 29.6 PPG this season (No. 2 in the NFL).
– Buffalo is surrendering 16.5 PPG this season (No. 2 in the NFL).


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Patriots vs Bills Prediction

The Patriots vs Bills NFL betting prediction uses the ESPN Football Power Index.

Patriots: 35.4%
Bills: 64.3%
Tie: 0.3%


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I am a simple Wisconsin man: I love beer and sports. I decided to create FlurrySports because I was sick of the politics and non-stories that the fat cat corporations put out. When you see football articles from me, just know that I combine my knowledge from playing, coaching, athletic training, and sports management/economic courses to give you a unique, but I feel well-rounded point of view. I am always down to talk about anything, so follow me on Twitter @FantasyFlurry if you decide you want more of me!

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