Among Sunday afternoon’s early NFL action this week is a cross-conference battle between the Carolina Panthers and Miami Dolphins. Both teams enter currently resting on the fringes of the playoff picture in their respective conferences. While both organizations have more of an eye towards the future than this season, a win would certainly be most welcome to close out the month of November. The NFL betting odds give the visitors a slight edge. Oddsmakers also expect this Panthers vs Dolphins game to be a defensive affair.

The following Panthers vs Dolphins NFL betting preview will give you the current odds, betting trends and picks for the Week 12 matchup, along with a stream link to watch games all season long.

Panthers vs Dolphins Week 12 NFL Betting Preview

NFL Regular Season — Week 12
Carolina Panthers (5-6, 3-2 Away) vs. Miami Dolphins (4-7, 2-3 Home)
Date: Sunday, Nov. 28, 2021
Time: 1 p.m. EST
Venue: Hard Rock Stadium — Miami Gardens, FL
Coverage: Click here for the stream

Carolina Panthers Preview

After starting the season off 3-0, the Panthers have now lost six of their last eight games coming into Sunday’s NFL betting contest. After throttling a shorthanded Arizona Cardinals team on the road two weeks ago, Carolina lost a heartbreaker to the Washington Football Team at home last week. Of course, the big headline surrounding the team these days is the return of former No. 1 overall draft pick and league MVP, Cam Newton. Last week’s loss certainly was no fault of Newton’s in his first start back with the Panthers. He accounted for three total touchdowns and actively got the team’s top two weapons, Christian McCaffrey and D.J. Moore, involved. Even at this point in his career, Newton is a quarterback upgrade over Sam Darnold.

Where the Panthers have fallen off a bit as the season has gone on is on defense. Particularly against the run, Carolina has gone from being a top-five adjusted defense to ranking outside the top-20. The trade acquisition to bring in Stephon Gilmore has helped keep the secondary sharp, but opponents have found success on the ground against the Panthers’ front. The offensive front has also struggled, giving up nearly 2.5 sacks per game. It will be interesting to see how the O-line holds up against the exotic defensive pressure packages of the Dolphins on Sunday.

Miami Dolphins Preview

The Dolphins’ season has followed almost the exact opposite trajectory of Carolina’s. After getting off to a 1-7 start, Miami enters this Week 12 NFL betting matchup on a three-game winning streak. Sure, two of those victories came over a pair of two-win teams. Even so, the Dolphins are clearly playing better football than they were earlier in the year. The defense has really taken a step forward. After containing the highly-regarded offense of the Buffalo Bills four weeks ago, the Dolphins have held each of their last three opponents to 17 or less. They have also forced seven turnovers during this winning streak. After being one of the best defenses at taking the ball away a season ago, Miami appears to be getting back to that.

After making a big statement on a national stage two weeks ago when he came on in relief, Tua Tagovailoa had another 273 yards passing and two touchdown strikes last Sunday. Rookie wideout Jaylen Waddle continues to be Tagovailoa’s go-to target. The former Alabama teammates connected eight times for 65 yards against the New York Jets last week. Tight end Mike Gesicki is also a tough task to contain. While Miami has struggled to run the ball with consistency this season, Myles Gaskin was quite productive in last week’s NFL betting win and cover. The Dolphins’ young offensive line continues to improve. If they can limit the Panthers’ pressure, the offense should be able to find ample success on Sunday.

Credit: Michael Reaves/Getty Images

Panthers vs Dolphins Odds and Spread

NFL betting odds for Panthers vs Dolphins are taken from BetMGM Sportsbook.

Moneyline: CAR: (-125) | MIA: (+105)
Spread: CAR: -1.5 (-110) | MIA: +1.5 (-110)
Total: 42 — Over: (-110) | Under: (-110)
Public (Spread) Betting Percentages via Action Network: CAR: (73%) | MIA: (27%)

Panthers vs Dolphins NFL Betting Trends

  • Panthers are just 2-6 ATS in their last eight games.
  • The total has gone under in 10 of the Panthers’ last 14 games.
  • Dolphins are 11-4 ATS in their last 15 home games.
  • Five of the Dolphins’ last six games have gone under the total.
  • Panthers are just 1-5 ATS in six previous head-to-head matchups against the Dolphins.

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Panthers vs Dolphins Stats

  • Carolina is averaging 20.5 points per game (PPG) this season (No. 22 in the NFL).
  • Carolina is surrendering 20.0 PPG this season (No. 6 in the NFL).
  • Miami is averaging 18.3 PPG this season (No. 26 in the NFL).
  • Miami is surrendering 24.5 PPG this season (No. 23 in the NFL).

Panthers vs Dolphins Prediction

This Panthers vs Dolphins NFL betting prediction uses NumberFire’s game projections. They give Carolina a 59.1% chance to win this Week 12 matchup.


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Henry’s passion for sports dates all the way back to childhood and has ultimately led to a full-fledged career as an analyst and content creator. After getting his start penning fantasy football articles, he forrayed into the betting side of the business in early 2019. His love for sports and statistics proved to be an ideal match with the dedicated research and strategy that handicapping requires. Henry currently specializes in betting analysis and picks for college football, college basketball and NASCAR. He counts the NFL, the WNBA, and NBA player props as additional leagues/markets of interest. Henry graduated from SUNY Buffalo in 2021 with a Communication Studies degree and a Psychology minor. A native of the Finger Lakes region in Upstate New York, he and his pup, Harold, have since relocated to Laramie, Wyoming. Thanks to his professional goals within the sports betting industry, there has been a whole lot of steam on the odds for a move to Las Vegas in 2023! Most of Henry’s free time is spent on outdoor adventures, playing chess, snowboarding, or reading a good book. He is also a competitive powerlifter and aspires to qualify for the USAPL Nationals meet within the next 2-3 years.

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