To kick off NFL Week 13, we have an NFC showdown between the Dallas Cowboys and New Orleans Saints. Both of these teams are hurting and in need of a win. They also both have key members of their team that will be missing from this game. In other words, anything could happen tonight. The following Cowboys vs Saints NFL betting preview will give you the current odds, betting trends and picks for the Week 13 matchup, along with a stream link to watch games all season long.
Cowboys vs Saints vs Cardinals TNF Week 13 NFL Betting Preview and Stream
NFL Regular Season — Week 13 Thursday Night Football
Dallas Cowboys (7-4, 3-2 Away) vs. New Orleans Saints (5-6, 2-3 Home)
Date: Thursday, December 2, 2021
Time: 8:20 p.m. EST
Venue: Caesars Superdome — New Orleans, LA
Coverage: Click here for the stream
The Cowboys are in an interesting position tonight, coming into this game without head coach Mike McCarthy, who is out with Covid. In his place, defensive coordinator Dan Quinn will serve as the head coach. We have seen in the past how he has struggled to be both the head coach and defensive play-caller. In fact, many of these struggles were against this Saints team. The good news for the Cowboys is they are expected to have all three of their wide receivers back on the field together. Given this is arguably the most talented receiving trio in the NFL, it should help this offense out a lot.
After sitting pretty at 5-2, the Saints have lost four games in a row. Clearly, something needs to change, and a big change is expected to take place. While the switch has not been confirmed, Taysom Hill has practiced as the starting quarterback for New Orleans this week. Given the lack of playmakers at receiver, it makes sense to switch to a mobile quarterback that allows this ground game to expand. While this will make the Saints look very different, will it yield a different result?

Cowboys vs Saints Odds & Spread
NFL betting odds for Cowboys vs Saints are taken from BetMGM Sportsbook.
Moneyline: DAL: (-205) | NO: (+172)
Spread: DAL: -4.5 (-106) | NO: +4.5 (-114)
Total: 47.5 — Over: (-105) | Under: (-115)
Public (Spread) Betting via Action Network: DAL: (41%) | NO: (59%)
Odds to Win Super Bowl LVI: DAL: (+1200) | NO: (+11000)
Cowboys vs Saints NFL Betting Trends
– Dallas is 8-3 against the spread (ATS) this season.
– The Over is 6-5 for the Cowboys this season.
– New Orleans is 5-6 ATS this season.
– The Over is 6-5 for the Saints this season.
Cowboys vs Saints Stats
– Dallas is averaging 29.6 points per game (PPG) this season (T-No. 2 in the NFL).
– Dallas is surrendering 22.7 PPG this season (T-No. 13 in the NFL).
– New Orleans is averaging 23.4 PPG this season (No. 18 in the NFL).
– New Orleans is surrendering 22.6 PPG this season (No. 12 in the NFL).
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Cowboys vs Saints Prediction
The Cowboys vs Saints NFL betting prediction uses the ESPN Football Power Index.
Cowboys: 54.5%
Saints: 45.1%
Tie: 0.4%

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