Football fans are in for a treat this Thursday night when the Indianapolis Colts travel to the Music City to take on the Tennessee Titans. This AFC South rivalry game has plenty more at stake than bragging rights. The winner will have the leg up in the division race as the push for the postseason heats up. The NFL odds and expert NFL picks favor the home team by the slimmest of margins ahead of this Thursday Night Football matchup.

This betting preview contains the NFL odds, key betting trends, prop bets, and best NFL picks for Colts vs Titans on Thursday night.

Credit: (AP Photo/AJ Mast)

NFL Odds, NFL Picks and NFL Props | Colts vs Titans

Colts vs Titans Game Info

Indianapolis Colts (5-3, 2-2 Away) at Tennessee Titans (6-2, 4-1 Home)
Date: Thursday, Nov. 12, 2020
Time: 8:20 p.m. EST
Venue: Nissan Stadium – Nashville, TN
Coverage: FOX, NFL Network
Attendance: About 10,000 fans will be allowed to attend.

Colts vs Titans NFL Odds + NFL Picks

Opening Lines: Titans -1.5; O/U 50.5
Moneyline: IND: (+115) | TEN: (-135)
Spread: IND: +2 (-110) | TEN: -2 (-110)
Total: 48.5 — Over: (-110) | Under: (-110)

All odds courtesy of Bovada Sportsbook

Colts vs Titans Overview

The Colts come into Thursday’s divisional showdown off a disappointing home loss to the Baltimore Ravens, a game that many people were calling their first true test of the season. Indianapolis outplayed the Ravens for the first half before failing to muster any offensive output over the final 30 minutes. Despite lacking a true go-to receiver, Philip Rivers has not been terrible this season. The Colts backfield is a revolving door lately, as Jordan Wilkins notched more carries than highly touted rookie Jonathan Taylor for the second straight week. Taylor failed to help his cause against Baltimore, coughing up a fumble that was returned for a Ravens’ touchdown.

The Titans managed to snap a two-game skid last week with a win over the Chicago Bears. Despite only completing 10 of 21 passes, Ryan Tannehill was able to connect with A.J. Brown for a handful of big plays and threw for two score in the win. Every bit of it was needed as the Bears bottled up Derrick Henry in a way that no prior Tennessee opponent this season was able to. Like Chicago, the Colts defense has been imposing their will on opponents all season. As good as the Titans offense has looked at times, it could be another uphill battle on Thursday night.

  • Colts 2020 Betting Trends: 4-4 ATS; 4-4 to the Over
  • Titans 2020 Betting Trends: 3-5 ATS; 5-2-1 to the Over
  • The Colts are 13-4 ATS in their last 17 games against the Titans, but only 3-3 in the last six.
  • The Under has cashed in three of the last five head-to-head meetings between the Colts and Titans.
  • The road team is 4-1 both straight up and ATS in the last five head-to-head meetings between the Colts and Titans.

Colts vs Titans Stats

  • Indianapolis has averaged 26.0 points per game (PPG) this season (No. 15 in the NFL)
  • Indianapolis has surrendered 20.0 PPG this season (No. 3 in the NFL)
  • Tennessee has averaged 29.0 PPG this season (No. 7 in the NFL)
  • Tennessee has surrendered 25.1 PPG this season (Tied for No. 15 in the NFL)

Monkey Knife Fight NFL Props

Monkey Knife Fight is a DFS site unlike DraftKings or FanDuel. Instead, the contests feature props to play, with varying multipliers for each contest. Unlike the aforementioned sites, you are only competing with yourself on MKF, and you do not need to worry about annoying salary caps.

Monkey Knife Fight has several great NFL props for both Thursday Night Football and the entire Week 10 slate. Here is one of my favorites for the Colts vs Titans game.

Ryan Tannehill has to contend with a much tougher defense Thursday night than Philip Rivers, but if Indianapolis is winning early, this could lead to a heavy-pass game script for Tennessee offensively. After a 128-yard performance two weeks ago, Corey Davis was shutout against the Bears while A.J. Brown had a monster game of his own. Davis has seen a solid target share in every other game he’s played this season and I would expect the two to be more comparable this week. Finally, Zach Pascal has seen six or more targets in four of the Colts’ last five games. Trey Burton has also seen a decent target floor, but I believe Pascal will have more opportunities on Thursday night.

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Colts vs Titans NFL Picks and NFL Odds

The spread for this game is yet to drift far from the opening number of Titans -1.5, perhaps unsurprisingly given the toss-up feel this AFC South game has. There has been early sharp money on the under though, as the total has come down a full two points from the opening 50.5.

While the Titans have been a predominantly Over team this season, betting primetime Unders has been a successful course for NFL bettors to follow. I’d much sooner see this game playing out similarly to Tennessee’s 20-17 win over Chicago last week than as a shootout. There is still value on the under for me even after the initial line move.

Indianapolis was as sharp as can be against the Ravens last week, with late line moves causing them to actually close as the favorite. While it proved to be the wrong side, I personally feel as though the Ravens are superior to the Titans, and we are getting a line that is essentially the exact same. Favorites of less than 3 points have been failing to cover at a high rate all season across the NFL. I’ll take my chances with the Colts once again. A moneyline bet is also in play.

NFL Picks: Colts +2, Under 48.5 (Both -110 at Bovada Sportsbook)


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Henry’s passion for sports dates all the way back to childhood and has ultimately led to a full-fledged career as an analyst and content creator. After getting his start penning fantasy football articles, he forrayed into the betting side of the business in early 2019. His love for sports and statistics proved to be an ideal match with the dedicated research and strategy that handicapping requires. Henry currently specializes in betting analysis and picks for college football, college basketball and NASCAR. He counts the NFL, the WNBA, and NBA player props as additional leagues/markets of interest. Henry graduated from SUNY Buffalo in 2021 with a Communication Studies degree and a Psychology minor. A native of the Finger Lakes region in Upstate New York, he and his pup, Harold, have since relocated to Laramie, Wyoming. Thanks to his professional goals within the sports betting industry, there has been a whole lot of steam on the odds for a move to Las Vegas in 2023! Most of Henry’s free time is spent on outdoor adventures, playing chess, snowboarding, or reading a good book. He is also a competitive powerlifter and aspires to qualify for the USAPL Nationals meet within the next 2-3 years.

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