One of the most heavily betted games on the NFL Week 6 slate is Cardinals vs Browns. The Cardinals will be looking to remain the only undefeated team in the NFL, while the Browns are looking to bounce back from a very deflating loss, giving up 26 points to the Chargers in the 4th quarter.
The line has moved half a point since it was announced the Cardinals will be without their head coach Kliff Kingsbury and multiple other members of the staff due to Covid protocol.
The following Cardinals vs Browns NFL betting preview will give you the current odds, betting trends and picks for the Week 6 matchup, along with a stream link to watch games all season long.
Cardinals vs Browns Week 6 NFL Betting Preview
NFL Regular Season — Week 6 Game
Arizona Cardinals (5-0, 3-0 Away) vs. Cleveland Browns (3-2, 2-0 Home)
Date: Sunday, October 17, 2021
Time: 4:05 p.m. EST
Venue: FirstEnergy Stadium — Cleveland, OH
Coverage: Click here for the stream
In this game, the Cardinals have a chance to prove they are as real as it gets. While they have earned a 5-0 record, many people still have questions and are hesitant to fully buy into this team. Though the questions are fair, there is no denying Kyler Murray and the Cardinals have gotten better every year. If they can roll into Cleveland without their coaches, win their sixth game in a row, and knock the Browns down to a .500 record, they will catapult themselves to the top of every power ranking there is.
The Browns need this game from both a record and a morale standpoint. They are just too many expectations on this team to be 3-3 after six weeks. They are facing some adversity of their own being without Nick Chubb, but luckily for Browns bettors, they have the best 1-2 punch in the entire NFL, and Kareem Hunt should have a great day.
The Browns are in a spot that typically sees a ton of public money behind it, but strangely it is relatively even. This should be a great game no matter which side you’re on.
Cardinals vs Browns Odds and Spread
NFL betting odds for Cardinals vs Browns are taken from BetMGM Sportsbook.
Moneyline: CLE: (-175) | ARI: (+150)
Spread: CLE: -3.5 (-105) | ARI: +3.5 (-115)
Total: 49 — Over: (-110) | Under: (-110)
Public (Spread) Betting via Action Network: CLE: (58%) | ARI: (42%)
Odds to Win Super Bowl LVI: CLE: (+1400) | ARI: (+1200)
Cardinals vs Browns NFL Betting Trends
– Arizona is 4-1 against the spread (ATS) this season.
– The Over is 2-3 for the Cardinals this season.
– Cleveland is 3-2 ATS this season.
– The Over is 3-2 for the Browns this season.
Cardinals vs Browns Stats
– Arizona is averaging 31.4 points per game (PPG) this season (No. 4 in the NFL).
– Arizona is surrendering 19 PPG this season (No. 6 in the NFL).
– Cleveland is averaging 28.4 PPG this season (T-No. 6 in the NFL).
– Cleveland is surrendering 22.8 PPG this season (No. 11 in the NFL).
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Cardinals vs Browns Prediction
The Cardinals vs Browns NFL betting prediction uses the ESPN Football Power Index.
Cardinals: 47.7%
Browns: 51.9%
Tie: 0.4%
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