A pair of AL East Division heavyweights will collide for the third of a four-game set this evening. Both the Toronto Blue Jays and New York Yankees carry 3-2 records into Wednesday night’s showdown in the Bronx. Each team has earned a win in this series so far. After Toronto picked up a shutout win on Monday, New York managed to return the favor last night. Given how loaded MLB betting analysts predict the division to be, even these early-season head-to-head matchups carry plenty of weight. Oddsmakers favor the home team by a fairly hefty amount ahead of tonight’s matchup. This prediction has a lot to do with the projected Blue Jays vs Yankees starting pitchers.

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Blue Jays vs Yankees Prediction and MLB Betting Preview

MLB Regular Season Game
Toronto Blue Jays (3-2, 1-1 Away) vs. New York Yankees (3-2, 3-2 Home)
Date: Wednesday, Apr. 13, 2022
Start Time: 7:05 p.m. EST
Venue: Yankee Stadium — Bronx, NY
Coverage: MLB Network

Blue Jays vs Yankees Starting Pitchers

Away Team: Jose Berrios (0-0 Record, 108.00 ERA)
Home Team: Gerrit Cole (0-0, 6.75 ERA)

Toronto Blue Jays Team Preview

Tuesday night saw the Blue Jays’ offense fail to generate a single run. Considering all of the talent that litters this lineup, such occurrences figure to be an anomaly over the course of the full MLB betting season. In fact, Toronto only mustered five total hits, two of which came courtesy of George Springer. The three total runs scored in the first two games of this series against the Yankees is less than the Blue Jays scored in each individual game of their opening series against Texas.

Speaking of that series against the Rangers, Jose Berrios certainly has to be itching to rebound. The 27-year-old took the mound for Toronto on Opening Day and failed to record more than a single out. Despite Berrios giving up three hits, two walks, a homer and four total runs in 1/3 of an inning, the Jays managed to rally and win the game. Given that the Yankees’ bats have been fairly quiet through five games, perhaps the righthander can bounce back tonight in the Bronx.

New York Yankees Team Preview

One of the biggest questions regarding the legitimacy of the Yankees as a championship contender coming into the season was the team’s pitching depth. Although it is early, the fact that New York earned a shutout win with No. 5 starter Nestor Cortes starting last night’s game is a positive sign. One night after being shut out, the Yankees returned the favor with a 4-0 win. D.J. LeMahieu and Gleyber Torres supplied four of the team’s seven total hits. Aaron Hicks also went yard as the Yankees snapped a mini two-game losing skid.

New York gets the nod from MLB betting oddsmakers as the favorite ahead of tonight’s game. One has to believe the fact that ace Gerrit Cole will be on the hill is a key component of this handicap. It is worth noting that the righthander was far from dominant in his own Opening Day outing last week. Cole ceded three runs on four hits to Boston and only lasted four innings. The matchup between the Yankees’ ace and the loaded Blue Jays lineup figures to be enthralling this evening.

Credit: Adam Hunger/AP Photo

Blue Jays vs Yankees MLB Betting Odds

MLB betting odds for Blue Jays vs Yankees are taken from Bovada Sportsbook.

Moneyline: TOR: (+141) | NYY: (-170)
Run Line: TOR: +1.5 (-145) | NYY: -1.5 (+125)
Total: 8 — Over: (-125) | Under: (+105)
Public Betting Percentages via Action Network: TOR: (55%) | NYY: (45%)

  • Blue Jays are 4-0 straight up in their last four games after scoring two runs or less in their previous game.
  • The UNDER is 6-0 in the Blue Jays’ last six games played on natural grass.
  • The UNDER is 4-0 in the Yankees’ last four games as a home favorite.
  • Each of the Yankees’ last five games as an MLB betting favorite with Gerrit Cole as their starter has gone OVER the total.
  • Blue Jays are 5-1 straight up in their last six head-to-head matchups against the Yankees in New York.

Blue Jays vs Yankees Stats

  • Toronto is averaging 4.60 runs per game (RPG) this season (No. 12 in the MLB).
  • Toronto is surrendering 5.40 RPG this season (No. 26 in the MLB).
  • New York is averaging 3.40 RPG this season (T-No. 21 in the MLB).
  • New York is surrendering 2.80 RPG this season (No. 5 in the MLB).

Blue Jays vs Yankees Weather Report

According to Forecast.io

Status: Cloudy
Temperature: 65℉
Humidity: 45%
Precipitation: 1%
Wind: 6 MPH (blowing right to left)

Blue Jays vs Yankees Prediction | MLB Betting Picks

Very few players have gotten off to as strong a start swinging the bat as George Springer. The Blue Jays outfielder enters Wednesday night’s matchup with a streak of four consecutive games with at least two hits. Springer has a .409 batting average on the young season thus far and also already has two home runs to his name.

While MLB betting oddsmakers are fully justified in favoring the Yankees due to the presence of Gerrit Cole as tonight’s starter, Springer actually has success against the veteran pitcher in his career. Springer has six total plate appearances against his former Houston Astros teammate. Four of those matchups have resulted in a hit. Springer has a pair of singles and two doubles off of Cole. Considering these historical numbers along with his torrid start to the 2022 season and a plus-money price on Springer to exceed 1.5 total bases is worth a look.

Blue Jays vs Yankees Prediction: George Springer Over 1.5 Total Bases (+129 at Bovada Sportsbook)


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Henry’s passion for sports dates all the way back to childhood and has ultimately led to a full-fledged career as an analyst and content creator. After getting his start penning fantasy football articles, he forrayed into the betting side of the business in early 2019. His love for sports and statistics proved to be an ideal match with the dedicated research and strategy that handicapping requires. Henry currently specializes in betting analysis and picks for college football, college basketball and NASCAR. He counts the NFL, the WNBA, and NBA player props as additional leagues/markets of interest. Henry graduated from SUNY Buffalo in 2021 with a Communication Studies degree and a Psychology minor. A native of the Finger Lakes region in Upstate New York, he and his pup, Harold, have since relocated to Laramie, Wyoming. Thanks to his professional goals within the sports betting industry, there has been a whole lot of steam on the odds for a move to Las Vegas in 2023! Most of Henry’s free time is spent on outdoor adventures, playing chess, snowboarding, or reading a good book. He is also a competitive powerlifter and aspires to qualify for the USAPL Nationals meet within the next 2-3 years.

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