Thanks to the highly anticipated return of Joe Burrow to New Orleans this Bengals vs Saints game will be one of the most talked about and watched games of the entire NFL Week 6 slate. The last time Burrow was inside the Superdome, he was hoisting a national championship trophy and smoking a cigar so smoothly it belongs in the Louvre.

The Saints have found themselves in back-to-back barnburners but may need to find a different way to beat the Bengals this week as they face a top-10 defense that has yet to hit an over this season.

This NFL betting preview will discuss our Bengals vs Saints prediction, NFL betting trends, odds and Week 6 NFL picks against the spread. But first, let’s take a look at this exciting NFL betting signup offer at BetOnline Sportsbook.

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Bengals vs Saints Prediction | Week 6 NFL Picks Against the Spread

Cincinnati Bengals (2-3, 1-2 Away) vs. New Orleans Saints (2-3, 1-2 Home)
Date: Sunday, Oct. 16, 2022
Time: 1:00 PM EST
Venue: Caesars Superdome — New Orleans, LA
Coverage: CBS

QB Comparison: Cincinnati – Joe Burrow (124/191, 1316 Yds, 9 TD, 5 INT) | New Orleans – Andy Dalton (36/52, 423 Yds, 2 TD, 1 INT)

The Bengals are slowly starting to look like the team that made a run to the Super Bowl last season. The offensive line is still atrocious, but Joe Burrow has not been sacked nearly as much in recent weeks. The Status of Tee Higgins will play a factor in this game, as the Bengals offense is nowhere near as good when he is not on the field. Their defense, on the other hand, has played very well, and will need to show up in a big way against a Saints team who has scored 64 points in the last two weeks. It should be an electric atmosphere, with a mixture of Joe Burrow-loving, LSU faithful, and die-hard Saints fans.

Andy Dalton has been a pleasant surprise for the Saints organization. Paying a veteran backup QB has paid off thus far, but his play is going to need to stay at the level we’ve seen if they want to beat this Bengals team. The return of Alvin Kamara has done wonders for this offense’s confidence and their ability to be effective. They are a dangerous unit no matter what defense they face. This game will likely come down to a costly turnover, or a missed opportunity, with the loser falling even further from playoff hope.

Credit: Dylan Buell/Getty Images

Bengals vs Saints Prediction, NFL Picks Against the Spread and Betting Odds

NFL betting odds for Bengals vs Saints are taken from BetOnline Sportsbook.

Moneyline: CIN: (-130) | NO: (+110)
Spread: 
CIN: -1 (-123) | NO: +1 (+103)
Total: 
43 — Over: (-110) | Under: (-110)
Public (Spread) Betting 
via Action NetworkCIN: (59%) | NO: (41%)

NFL Betting Trends for Bengals vs Saints

  • The Bengals are 3-2 in NFL picks against the spread (ATS) this season.
  • The OVER is 0-5 in Cincinnati’s games this season.
  • The Saints are 2-3 in NFL picks ATS this season.
  • The OVER is 3-2 in New Orleans’s games this season.

Bengals vs Saints Stats

  • Cincinnati averages 21.6 points per game (PPG) this season (T-No. 16 in the NFL).
  • Cincinnati surrenders 17.8 PPG this season (No. 8 in the NFL).
  • New Orleans averages 23 PPG this season (T-No. 12 in the NFL).
  • New Orleans surrenders 25.6 PPG this season (T-No. 26 in the NFL).

Bengals vs Saints Prediction

This Week 6 NFL betting Jets vs Packers prediction uses NumberFire’s game projections. They give Cincinnati a 63% chance to win this Week 6 matchup.

The FlurrySports experts also have their own Week 6 NFL Picks here.


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