In a Second Round NCAA Tournament game, the (3) Xavier Musketeers will face off with the (11) Pittsburgh Panthers in the Midwest Region. Let’s take a look at the top college basketball betting odds, March Madness expert picks, betting trends and KenPom Rankings, then give our Xavier vs Pittsburgh prediction. 

Xavier vs Pittsburgh Prediction and March Madness Expert Picks

2023 NCAA Tournament
No. 3 Xavier Musketeers (26-9) vs No. 11 Pittsburgh Panthers (24-11)
Date: Sunday, March 19, 2023
Time: 12:10 P.M. EST
Venue: Greensboro Coliseum – Greensboro, NC
Coverage: CBS

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Xavier vs Pittsburgh March Madness Betting Odds

All college basketball betting odds for Xavier vs Pittsburgh can be found at BetUS Sportsbook.

Moneyline: PITT: (+175) | XAV: (-210)
Point Spread: PITT: +5 (-110) | XAV: -5 (-110)
Total: 151.5 – OVER: (-110) | UNDER: (-110)


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KenPom Rankings | Bracketology

KenPom Rankings are from KenPom.com

TeamAdjEM (Rk)AdjO (Rk)AdjD (Rk)AdjT (Rk)
Xavier+19.64 (16)118.8 (8)99.1 (72)70.4 (38)
Pittsburgh+12.79 (62)114.6 (27)101.8 (108)67.2 (182)
  • Xavier is 18-16-1 against the spread (ATS) this season.
  • Pittsburgh is 24-10-1 ATS this season.
  • The OVER is 21-13-1 for Xavier this season.
  • The OVER is 21-14 for Pittsburgh this season.

Xavier vs Pittsburgh Prediction | March Madness Expert Picks

I think that Pittsburgh’s last win over Iowa State was a testimate to the poor game that the Cyclones played, as opposed to how good Pittsburgh played. In that game though, Pittsburgh’s defense made life very difficult for Iowa State at times. Xavier was another team that struggled throughout the entire game in their first-round matchup against Kennesaw State. The offense did not look the eighth-ranked offense in the country in that game. Xavier has shown all season that they can score the ball and I don’t think one bad game should have too big of an effect on this team. Pittsburgh struggled on the defensive side of the ball at times this season, proved by their 108 ranking in KenPom for defense efficiency.

Xavier is a better team than Pittsburgh, so seeing that Xavier plays at such a higher pace, one has to believe that Xavier will control the flow of this game. If that is the case, Pittsburgh could find itself down early. Pittsburgh has proved time and time again though that they can stay in games and cover the spread. I like that here, as Xavier is clearly the better team, but Pittsburgh has found some sort of success on the defensive side of the ball.

Our official college basketball betting Xavier vs Pittsburgh prediction will be Pittsburgh COVERS at BetUS

For what it’s worth, the ESPN Matchup Predictor gives Xavier a 68.8% chance to win.


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From Green Bay, Wisconsin. NBA, College Basketball, MLB and NFL Fan/Writer. UW-La Crosse Graduate. Watch Sports, Play Basketball and Travel in Free Time. Love to go Fishing. Go Tar Heels.

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