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Fantasy Football Playoffs Strength of Schedule: Indianapolis Colts

Seahawks vs Colts NFL Betting Odds, Trends and Picks for Week 1

Zach Brunner by Zach Brunner
September 7, 2021
in Betting, NFL
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Both the Seattle Seahawks and Indianapolis Colts endured some quarterback drama this offseason. For Seattle, Russell Wilson voiced his frustration and was even rumored to be traded to the Colts at one point. In Indianapolis, Philip Rivers had retired, and they decided to trade for Carson Wentz, giving him a second chance in the NFL. After this drama, which team will look the most cohesive in this Seahawks vs Colts Week 1 NFL betting matchup?

The following Seahawks vs Colts NFL betting preview will give you the current odds, betting trends and picks for the Week 1 matchup.

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Seahawks vs Colts Week 1 NFL Betting Preview

NFL Regular Season — Week 1 Game
Seattle Seahawks (0-0, 0-0 Away) vs. Indianapolis Colts (0-0, 0-0 Home)
Date: Sunday, September 12, 2021
Time: 1:00 p.m. EST
Venue: Lucas Oil Stadium — Indianapolis, IN
Coverage: FOX

After an offseason that featured some quarterback drama, Russell Wilson and the Seattle Seahawks look ready to compete again. However, they must be sharper for them to compete in the NFC West. Offensively, Seattle looks prepared to open it up more, giving Wilson the freedom to air it out. Defensively, there are still holes, but playmakers like Jamal Adams and Bobby Wagner allow them to be opportunistic. 

The Colts experienced a lot of change on the offensive side of the football. It starts with Carson Wentz at quarterback. Indianapolis is clearly taking a gamble on the former Philadelphia Eagles passer. Unfortunately, they aren’t surrounding him with much talent to give him a chance to succeed. The wide receiver corps is weak, and it becomes weaker without T.Y. Hilton to start the season. The offensive line also has plenty of question marks, which is bad news, given the injury history of Wentz. 

Indianapolis will pride itself on its defense. Darius Leonard will continue to fly around and make plays. DeForest Buckner will control the interior offensive line. This is also an underrated secondary, especially if Indianapolis is able to generate pressure up front.

seahawks vs colts nfl betting trends odds picks
Credit: Julio Aguilar/Getty Images

Seahawks vs Colts Odds & Spread

NFL betting odds for Seahawks vs Colts are taken from FanDuel Sportsbook.

Moneyline: SEA: (-142) | IND: (+120)
Spread: SEA: -2.5 (-110) | IND: +2.5 (-110)
Total: 49.5 — Over: (-112) | Under: (-108)
Public (Spread) Betting Percentages via oddsFire: SEA: (41%) | IND: (59%)
Odds to Win Super Bowl LVI: SEA: (+2000) | IND: (+3300)

Seahawks vs Colts NFL Betting Trends

– Seattle went 8-9 against the spread (ATS) last season.
– The over was 8-9 for the Seahawks last season.
– Indianapolis went 9-8 ATS last season.
– The over was 10-7 for the Colts last season.

Seahawks vs Colts Stats

– Seattle averaged 28.2 points per game (PPG) last season (No. 7 in the NFL).
– Seattle surrendered 23.6 PPG last season (No. 16 in the NFL).
– Indianapolis averaged 27.9 PPG last season (No. 8 in the NFL).
– Indianapolis surrendered 22.9 PPG last season (T-No. 11 in the NFL).

Seahawks vs Colts Prediction

The Seahawks vs Colts NFL betting prediction uses the NumberFire Picks tool.

Seahawks -2.5: 44.1%
Colts +2.5: 55.9%


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Tags: Bobby WagnerCarson WentzDarius LeonardDeForest BucknerIndianapolis ColtsJamal AdamsNFLNFL BettingRussell WilsonSeattle SeahawksSports BettingT.Y. Hilton
Zach Brunner

Zach Brunner

I am a simple Wisconsin man: I love beer and sports. I decided to create FlurrySports because I was sick of the politics and non-stories that the fat cat corporations put out. When you see football articles from me, just know that I combine my knowledge from playing, coaching, athletic training, and sports management/economic courses to give you a unique, but I feel well-rounded point of view. I am always down to talk about anything, so follow me on Twitter @FantasyFlurry if you decide you want more of me!

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