For the third time this season, the Seattle Seahawks will take on the San Francisco 49ers. However, this time the stakes are higher, as it’s a win-or-go-home NFL Playoffs matchup. Let’s take a look at the NFL Playoffs Wild Card Weekend betting preview for this game, including odds, trends, picks against the spread and a Seahawks vs 49ers prediction. But first, check out this incredible BetMGM Wild Card Weekend promo!
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Seahawks vs 49ers Prediction | NFL Playoffs Wild Card Weekend Preview
NFL Playoffs — Wild Card Weekend
Seattle Seahawks (9-8, 4-4 Away) vs. San Francisco 49ers (13-4, 8-1 Home)
Date: Saturday, January 14, 2022
Time: 4:30 p.m. EST
Venue: Levi’s Stadium — Santa Clara, CA
Coverage: FOX
Seahawks vs 49ers Odds & Spread
NFL betting odds for Seahawks vs 49ers are taken from BetMGM Sportsbook.
Moneyline: SEA: (+375) | SF: (-500)
Spread: SEA: +9.5 (-110) | SF: -9.5 (-110)
Total: 42 — Over: (-110) | Under: (-110)
Public (Spread) Betting via Action Network: SEA: (41%) | SF: (59%)
Odds to Win Super Bowl LVII: SEA: (+10000) | SF: (+450)
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NFL Betting Trends for Seahawks vs 49ers
- The Seahawks are 7-10 in NFL picks against the spread (ATS) this season.
- The OVER is 8-9 in Seattle’s games this season.
- The 49ers are 11-6 in NFL picks ATS this season.
- The OVER is 9-8 in San Francisco’s games this season.
Seahawks vs 49ers Stats
- Seattle averages 23.9 points per game (PPG) this season (No. 9 in the NFL).
- Seattle surrenders 23.6 PPG this season (No. 25 in the NFL).
- San Francisco averages 26.5 PPG this season (No. 6 in the NFL).
- San Francisco surrenders 16.3 PPG this season (No. 1 in the NFL).
Seahawks vs 49ers Prediction
This NFL Playoffs betting Seahawks vs 49ers prediction uses NumberFire’s game projections. They give San Francisco a 74.7% chance to win this Wild Card Weekend matchup.
The FlurrySports experts also have their own NFL picks for the playoffs here.
NFL Playoffs Schedule | Super Wild Card Weekend
Saturday Games
Seattle Seahawks vs San Francisco 49ers
- 4:35 pm ET, FOX
Los Angeles Chargers vs Jacksonville Jaguars
- 8:15 pm ET, NBC
Sunday Games
Miami Dolphins vs Buffalo Bills
- 1:05 pm ET, CBS
New York Giants vs Minnesota Vikings
- 4:40 pm ET, FOX
Baltimore Ravens vs Cincinnati Bengals
- 8:15 pm ET, NBC
Monday Games
Dallas Cowboys vs Tampa Bay Buccaneers
- 8:15 pm ET, ESPN
On Bye: Philadelphia Eagles, Kansas City Chiefs
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