In a First Round NCAA Tournament game, the 5-seed Saint Mary’s Gaels will face off with the 12-seed Indiana Hoosiers in the East Region. Let’s take a look at the top college basketball betting odds, picks, bracketology, betting trends and KenPom Rankings, then give our Saint Mary’s vs Indiana prediction for the game today. 

Saint Mary’s vs Indiana | NCAA Tournament Bracketology

2022 NCAA Tournament
No. 5 Saint Mary’s Gaels (25-7) vs. No. 12 Indiana Hoosiers (21-13)
Date: Thursday, March 17, 2022
Time:7:20 PM EST
Venue: Moda Center — Portland, OR
Coverage: TBS

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Saint Mary’s vs Indiana College Basketball Betting Picks and Odds

All college basketball betting odds for Saint Mary’s vs Indiana can be found at BetUS Sportsbook.

Moneyline: SMC: (-155) | IU: (+135)
Point Spread: SMC: -3.5 (-110) | IU: +3.5 (-110)
Total: 126.5 — Over: (-110) | Under: (-110)


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Credit: AP Photo/Rick Scuteri

KenPom Rankings | Bracketology

KenPom Rankings are from KenPom.com

TeamRkAdjOAdjDAdjT
Saint Mary’sNo. 16109.8 (No. 63)90.0 (No. 9)63.5 (No. 338)
IndianaNo. 36107.6 (No. 91)92.6 (No. 21)67.0 (No. 185)
  • Gaels are 6-0 ATS in their last six games following a straight up loss.
  • The total has gone OVER in each of the Gaels’ last five games following a straight up loss.
  • The UNDER is 7-1 in the Gaels’ last eight NCAA Tournament games.
  • Hoosiers are 5-0 ATS in their last five games overall.
  • Hoosiers are 4-0 ATS in their last four games as an underdog.
  • In their last five games against teams with a winning record, the Hoosiers are 5-0 ATS.

Saint Mary’s vs Indiana Prediction | March Madness Picks and Bracketology

Indiana was already a part of the NCAA Tournament First Four as a result of being seen as one of the “Last Four Teams In”. IU took care of a reeling Wyoming team that lost the game as much or more so than the Hoosiers actually won it. Nonetheless, Mike Woodson has his alma mater in the main bracket in his first year at the helm. However, a two-day turnaround with a long flight from Dayton to Portland in between is far from the ideal scheduling situation.

Where Indiana will have a distinct advantage over West Coast Conference representative Saint Mary’s is in terms of depth. In total, ten different Hoosiers averaged at least 10 minutes per game over the course of the full season. IU’s depth played a key role in the First Four matchup against a Wyoming team that largely only utilizes a six-man rotation. While leading scorer Trayce Jackson-Davis went off for 29 points and nine rebounds, Indiana also got quality minutes and 15 points from Jordan Geronimo among other reserves.

Unfortunately for Indiana, this Saint Mary’s team is completely legit. The Gaels are a senior-laden team and are a force to be reckoned with defensively. KenPom lists Randy Bennett’s squad as a top-10 defensive team that also plays at one of the 25 slowest tempos in all of college basketball. In Matthias Tass, Saint Mary’s has a sound big man to counteract the Hoosiers’ size in the frontcourt. With Tommy Kuhse providing a calming presence at point guard, look for the Gaels to dissect IU thoroughly in this one.

Our college basketball betting Saint Mary’s vs Indiana prediction tonight will be Saint Mary’s -3.5 at BetUS

For what it’s worth, the ESPN Matchup Predictor gives Saint Mary’s a 57.5% chance to win.


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Henry’s passion for sports dates all the way back to childhood and has ultimately led to a full-fledged career as an analyst and content creator. After getting his start penning fantasy football articles, he forrayed into the betting side of the business in early 2019. His love for sports and statistics proved to be an ideal match with the dedicated research and strategy that handicapping requires. Henry currently specializes in betting analysis and picks for college football, college basketball and NASCAR. He counts the NFL, the WNBA, and NBA player props as additional leagues/markets of interest. Henry graduated from SUNY Buffalo in 2021 with a Communication Studies degree and a Psychology minor. A native of the Finger Lakes region in Upstate New York, he and his pup, Harold, have since relocated to Laramie, Wyoming. Thanks to his professional goals within the sports betting industry, there has been a whole lot of steam on the odds for a move to Las Vegas in 2023! Most of Henry’s free time is spent on outdoor adventures, playing chess, snowboarding, or reading a good book. He is also a competitive powerlifter and aspires to qualify for the USAPL Nationals meet within the next 2-3 years.

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