In the recent past, a Patriots vs Packers game was viewed as a rare treat, featuring two of the greatest quarterbacks of all time. Those legendary Tom Brady vs Aaron Rodgers games are a far cry from what we will see on the field at Lambeau this Sunday afternoon, as the Green Bay Packers will face long-time New England Patriots back-up and journeyman Brian Hoyer, who makes his first start since October 2020.

This NFL betting preview will discuss our Patriots vs Packers prediction, NFL betting trends, odds and Week 4 NFL picks against the spread. But first, let’s take a look at this exciting NFL betting signup offer at BetOnline Sportsbook.

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Patriots vs Packers Prediction | Week 4 NFL Picks Against the Spread

New England Patriots (1-2, 1-1 Away) vs. Green Bay Packers (2-1, 1-0 Home)
Date: Sunday, Oct. 2, 2022
Time: 4:25 PM EST
Venue: Lambeau Field — Green Bay, WI
Coverage: CBS

QB Comparison: Patriots – Brian Hoyer (0/0, – Yds, – TD, – INT) | Green Bay – Aaron Rodgers (68/94, 684 Yds, 4 TD, 2 INT)

Things are looking grim for the Patriots, who are without their young starting QB in Mac Jones. They will likely drop to 1-3 after this week. It’s still early, but in a division now ruled by Buffalo, there is little hope as New England navigates their way into a postseason berth. Patriots fans rest assured, Bill Belichick will have his guys prepared to the best of his ability. Unfortunately for them, they are starting a quarterback who is 0-11 in his last 11 starts.

The Packers offense has not yet fully figured out who they are. The flash of ability rookie Romeo Doubs (8 rec, 73 yds, 1 td) showed last week is a great sign for the future, but can not be relied upon yet on a week-to-week basis. The Packers’ biggest problem this season has been an inability to move the ball on offense in the second half. Last week, Green Bay was about to go up 21-3 on the Buccaneers, but Aaron Jones fumbled and the Packers did not score a single point the rest of the way.

Their defense was able to limit the damage and cling to a two-point victory. However, the “score and stall” offense is not a long-term recipe for winning football games. With the best defense Green Bay has seen in a decade getting to tee off on turnover-prone Brian Hoyer, the offense should have plenty of chances to put points on the board and cover the spread.

Credit: Tom Pennington/Getty Images

Patriots vs Packers Prediction, NFL Picks Against the Spread and Betting Odds

NFL betting odds for Patriots vs Packers are taken from BetOnline Sportsbook.

Moneyline: NE: (+345) | GB: (-425)
NE: +9.5 (-110) | GB: -9.5 (-110)
40 — Over: (-110) | Under: (-110)
Public (Spread) Betting 
via Action NetworkNE: (47%) | GB: (53%)

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NFL Betting Trends for Patriots vs Packers

  • The Patriots are 0-2-1 in NFL picks against the spread (ATS) this season.
  • The OVER is 1-2 in New England’s games this season.
  • The Packers are 2-1 in NFL picks ATS this season.
  • The OVER is 0-3 in Green Bay’s games this season.

Patriots vs Packers Stats

  • New England averages 16.7 points per game (PPG) this season (No. 25 in the NFL).
  • New England surrenders 23.7 PPG this season (No. 22 in the NFL).
  • Green Bay averages 16 PPG this season (No. 27 in the NFL).
  • Green Bay surrenders 15.0 PPG this season (No. 5 in the NFL).

Patriots vs Packers Prediction

This Week 4 NFL betting Patriots vs Packers prediction uses NumberFire’s game projections. They give Green Bay a 66% chance to win this Week 4 matchup.

The FlurrySports experts also have their own Week 4 NFL Picks here.

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