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Cardinals vs Titans NFL Betting Odds, Trends and Picks for Week 1

Both the Arizona Cardinals and Tennessee Titans made notable additions this offseason in hopes of competing now. However, these offenses play very different styles of football. Arizona wants to spread out the defense and pass it around, while Tennessee wants to run downhill at you. Which style will prevail in the Cardinals vs Titans NFL betting matchup?

The following Cardinals vs Titans NFL betting preview will give you the current odds, betting trends and picks for the Week 1 matchup.

Cardinals vs Titans Week 1 NFL Betting Preview

NFL Regular Season — Week 1 Game
Arizona Cardinals (0-0, 0-0 Away) vs. Tennessee Titans (0-0, 0-0 Home)
Date: Sunday, September 12, 2021
Time: 1:00 p.m. EST
Venue: Nissan Stadium — Nashville, TN
Coverage: CBS

The Cardinals added weapons on both sides of the football, telling us they are looking to compete right now. Someone tell them that they are the odds favorite to lose their division. Kyler Murray proves to be electric with his legs, but he leaves a lot to be desired as a passer. The offensive line for Arizona also isn’t great. Defensively, the headline acquisition was J.J. Watt, but it may be the rookie Zaven Collins who becomes the biggest game-changer newcomer. If the defense can get off the field and put Murray in positive field position, they may be able to surprise some people and prove head coach Kliff Kingsbury isn’t over his head. 

The Titans are mostly running things back this season, with a couple added exceptions. They replace Corey Davis at wide receiver with Julio Jones — not bad. Still, the obvious weakness of this team last season was the defense. The addition of Bud Dupree is big, but a strong passing team will likely have little trouble with the Titans’ defense. They shouldn’t be done adding talent to that side of the ball.

nfl betting odds picks trends cardinals vs titans
Credit: Wesley Hitt/Getty Images

Cardinals vs Titans Odds & Spread

NFL betting odds for Cardinals vs Titans are taken from FanDuel Sportsbook.

Moneyline: ARI: (+130) | TEN: (-154)
Spread: ARI: +3 (-114) | TEN: -3 (-105)
Total: 52 — Over: (-110) | Under: (-110)
Public (Spread) Betting Percentages via oddsFire: ARI: (41%) | TEN: (59%)
Odds to Win Super Bowl LVI: ARI: (+4800) | TEN: (+2500)

Cardinals vs Titans NFL Betting Trends

– Arizona went 7-9 against the spread (ATS) in its 16 games last season.
– The game totals were 5-11 in favor of the over for Arizona last season.
– Tennessee went 7-10 ATS in its 17 games last season.
– The game totals were 12-4-1 in favor of the over for Tennessee last season.

Cardinals vs Titans Stats

– Arizona averaged 25.6 points per game (PPG) last season (No. 14 in the NFL).
– Arizona surrendered 22.9 PPG last season (T-No. 11 in the NFL).
– Tennessee averaged 29.6 PPG last season (No. 4 in the NFL).
– Tennessee surrendered 27.0 PPG last season (No. 24 in the NFL).

Cardinals vs Titans Prediction

The Cardinals vs Titans NFL betting prediction uses the NumberFire Picks tool.

Cardinals +3: 40.7%
Titans -3: 50.5%
Push: 8.8%


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