Two divisional rivals trending in opposite directions will take center stage on Thursday Night Football this week when the Seattle Seahawks host the Arizona Cardinals. Despite the absence of the “12th Man” at CenturyLink Field, there will be plenty of noise surrounding this game thanks to both teams being involved in a nip and tuck race for the NFC West division crown. The NFL odds and expert NFL picks for the game offer a slight edge to the home team.

This betting preview contains the NFL odds, key betting trends, prop bets, and best NFL picks for Cardinals vs Seahawks on Thursday night.

NFL Odds, NFL Picks and NFL Props | Cardinals vs Seahawks

Cardinals vs Seahawks Game Info

Arizona Cardinals (6-3, 3-1 Away) at Seattle Seahawks (6-3, 4-0 Home)
Date: Thursday, Nov. 19, 2020
Time: 8:20 p.m. EST
Venue: CenturyLink Field – Seattle, WA
Coverage: FOX, NFL Network
Attendance: No fans will be allowed to attend.

Credit: Jamie Squire/Getty Images

Cardinals vs Seahawks NFL Odds + NFL Picks

Opening Lines: Seahawks -5.5; O/U 56.5
Moneyline: : ARI: +3 (-110) | SEA: -3 (-110)
Spread: ARI: (+140) | SEA: (-160)
Total: 57.5 — Over: (-110) | Under: (-110)

All odds courtesy of Bovada Sportsbook

Cardinals vs Seahawks Overview

The Cardinals have been the toast of the league this week. On what very well could’ve been the play of the year, MVP candidate Kyler Murray’s Hail Mary heave was caught by DeAndre Hopkins in the end zone resulting in a miracle win over the Buffalo Bills. The whirlwind continues for Kliff Kingsbury’s squad, and the quick turnaround to play on Thursday night makes them tough to trust for some expert NFL picks analysts. Of course, it was the Cardinals who put an end to an undefeated Seattle start with their comeback OT win just four weeks ago. Murray, Hopkins, Christian Kirk and the bevy of offensive weapons will look to run roughshod over the porous Seattle defense once again on Thursday night.

From 5-0 to 6-3, there is suddenly cause for concern in the Pacific Northwest. Russell Wilson’s MVP case is drying up quickly after throwing seven interceptions in the Seahawks’ last four games, including three against the Cardinals in Week 7. Seattle figures to have reinforcements returning to the backfield Thursday in the form of Chris Carson and Carlos Hyde. With that said, wideout Tyler Lockett missed practice on Monday and Tuesday with a knee injury. This is particularly concerning when it comes to the NFL odds and NFL picks for this game given the phenomenal job Patrick Peterson did in blanketing D.K. Metcalf the first time these teams met.

Cardinals vs Seahawks Betting Trends

  • Cardinals 2020 Betting Trends: 5-4 ATS; 3-6 to the Over
  • Seahawks 2020 Betting Trends: 5-4 ATS; 6-3 to the Over
  • The Cardinals are 5-1 ATS in their last six head-to-head meetings against the Seahawks.
  • Road teams are 11-3-1 straight up in the last 15 head-to-head meetings between the Cardinals and Seahawks.
  • Six of the last nine head-to-head meetings between the Cardinals and Seahawks have been decided by three points or less.

Cardinals vs Seahawks Stats

  • Arizona has averaged 29.6 points per game (PPG) this season (Tied for No. 6 in the NFL)
  • Arizona has surrendered 23.3 PPG this season (No. 9 in the NFL)
  • Seattle has averaged 32.2 PPG this season (No. 1 in the NFL)
  • Seattle has surrendered 29.6 PPG this season (No. 28 in the NFL)

Monkey Knife Fight NFL Props

Monkey Knife Fight is a DFS site unlike DraftKings or FanDuel. Instead, the contests feature props to play, with varying multipliers for each contest. Unlike the aforementioned sites, you are only competing with yourself on MKF, and you do not need to worry about annoying salary caps.

Monkey Knife Fight has several great NFL props for both Thursday Night Football and the entire Week 11 slate. Here is one of my favorites for the Cardinals vs Seahawks game.

Before you call me crazy for selecting both quarterbacks of all players for this rushing yards prop, hear me out. Kyler Murray gets his on the ground each and every week. He has double digit rushing attempts in each of the last four games and has rushed for 67 yards or more in all but two games on the season. His 14 rush attempts against the Seahawks four weeks ago were the most he’s had in a game this year.

Meanwhile, Russell Wilson had his season-high in rushing yards the first time these two teams met with 84. The outlook for NFL picks and NFL props involving the Seahawks backfield is complicated by the unknown status of Chris Carson as he continues to recover from a foot injury. I think both QBs have to make plays with their legs to extend drives in what figures to be a pass-heavy game. Murray will get his, and if Carson is out or limited, Wilson should be able to make up the difference.

Successfully drafting two players to exceed the rushing yards total would win you 2x your buy-in.

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Cardinals vs Seahawks NFL Picks and NFL Odds

The NFL odds for this game are projecting another shootout between these offense-first teams and rightfully so. Expert NFL picks have moved the market up a full point from the opening total of 56.5, while the Cardinals have seen some sharp money in their favor on the spread. It’s worth opening that the line was originally Seahawks -5.5 on the lookahead and reopened at -3.5 after Sunday’s games.

While I tend to lean towards Seattle successfully avenging their loss in Arizona from four weeks ago, the status of Tyler Lockett cannot be understated. He was crucial to the Seahawks’ offensive attack in that game, with 15 catches on 20 targets for 200 yards and three scores. If he is out, Russell Wilson will immediately be up against it as he looks to get back on track and cover the NFL odds.

With that said, I lean towards the simple contrarian NFL picks play of betting the total under. Seattle showed marked improvement defensively against the Rams last week, and I expect the unit to again step up in what could almost be considered a must-win at home in terms of the division race. Add in a potential hangover effect for the Cardinals’ offense after last week’s heroics and there are multiple NFL picks angles pointing towards fewer points in this game than the public might perceive.

Pick: Under 57.5 Total Points (-110 at Bovada Sportsbook)

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Henry’s passion for sports dates all the way back to childhood and has ultimately led to a full-fledged career as an analyst and content creator. After getting his start penning fantasy football articles, he forrayed into the betting side of the business in early 2019. His love for sports and statistics proved to be an ideal match with the dedicated research and strategy that handicapping requires. Henry currently specializes in betting analysis and picks for college football, college basketball and NASCAR. He counts the NFL, the WNBA, and NBA player props as additional leagues/markets of interest. Henry graduated from SUNY Buffalo in 2021 with a Communication Studies degree and a Psychology minor. A native of the Finger Lakes region in Upstate New York, he and his pup, Harold, have since relocated to Laramie, Wyoming. Thanks to his professional goals within the sports betting industry, there has been a whole lot of steam on the odds for a move to Las Vegas in 2023! Most of Henry’s free time is spent on outdoor adventures, playing chess, snowboarding, or reading a good book. He is also a competitive powerlifter and aspires to qualify for the USAPL Nationals meet within the next 2-3 years.

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