Capping off a packed NFL Week 5 Sunday will be the Buffalo Bills taking on the Kansas City Chiefs. With the highest NFL betting total of the week, this is expected to be an extremely exciting game with plenty of offensive fireworks.

The following Bills vs Chiefs NFL betting preview will give you the current odds, betting trends and picks for the Week 5 matchup, along with a stream link to watch games all season long.

Bills vs Chiefs SNF Week 5 NFL Betting Preview and Stream

NFL Regular Season — Week 5 Sunday Night Football
Buffalo Bills (3-1, 1-0 Away) vs. Kansas City Chiefs (2-2, 1-1 Home)
Date: Sunday, October 10, 2021
Time: 8:20 p.m. EST
Venue: GEHA Field at Arrowhead Stadium — Kansas City, MO
Coverage: Click here for the stream

After losing to the Steelers in Week 1, the Bills have been the most dominant team in the NFL. They have outscored their opponents 118-21 over the past three weeks. Yes, the competition hasn’t been great, but their level of focus still proves how good this team is. Offensively, they are more of a balanced attack overall this season, running the football and targeting more receiving options. Defensively, they’ve had two shutouts over the past three weeks. We still need to see more from them, but they have done everything that has been asked, recently.

The Chiefs are coming off a dominant win, but it was against the Eagles. The truth of the matter is, the Chiefs are 2-2 and haven’t shown title-contending play thus far. The offense hasn’t been the problem, led by Patrick Mahomes and his talented group of pass-catcher. By the way, this is a group that will get better this week, with the debut of Josh Gordon. Anyways, it’s the defense that is the massive issue in Kansas City. They have surrendered a league-worst 6.9 yards per play. They must find a way to get off the field so Mahomes can get the ball in his hands.

Credit: Rob Carr/Getty Images

Bills vs Chiefs Odds & Spread

NFL betting odds for Bills vs Chiefs are taken from BetMGM Sportsbook.

Moneyline: BUF: (+134) | KC: (-158)
Spread: BUF: +3 (-110) | KC: -3 (-110)
Total: 56.5 — Over: (-110) | Under: (-110)
Public (Spread) Betting via Action Network:
 BUF: (46%) | KC: (54%)
Odds to Win Super Bowl LVI: BUF: (+850) | KC: (+550)

Bills vs Chiefs NFL Betting Trends

– Buffalo is 3-1 against the spread (ATS) this season.
– The Over is 1-3 for the Bills this season.
– Kansas City is 1-3 ATS this season.
– The Over is 3-1 for the Chiefs this season.

Bills vs Chiefs Stats

– Buffalo is averaging 33.5 points per game (PPG) this season (T-No. 2 in the NFL).
– Buffalo is surrendering 11.0 PPG this season (No. 1 in the NFL).
– Kansas City is averaging 33.5 PPG this season (T-No. 2 in the NFL).
– Kansas City is surrendering 31.2 PPG this season (No. 31 in the NFL).


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Bills vs Chiefs Prediction

The Bills vs Chiefs NFL betting prediction uses the ESPN Football Power Index.

Buccaneers: 56.6%
Patriots: 43.1%
Tie: 0.3%


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I am a simple Wisconsin man: I love beer and sports. I decided to create FlurrySports because I was sick of the politics and non-stories that the fat cat corporations put out. When you see football articles from me, just know that I combine my knowledge from playing, coaching, athletic training, and sports management/economic courses to give you a unique, but I feel well-rounded point of view. I am always down to talk about anything, so follow me on Twitter @FantasyFlurry if you decide you want more of me!

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