The marquee NFL game of the Week 14 late-afternoon window features the Buffalo Bills traveling down to the Sunshine State to face the Tampa Bay Buccaneers. While both teams’ fanbases came into the season with Super Bowl aspirations, only one of these clubs has proven to be deserving of the hype thus far. Sunday’s matchup looms particularly large for the visitors when it comes to the current playoff standings. However, the NFL betting odds have named the home side as the favorite ahead of this Bills vs Buccaneers showdown.

The following Bills vs Buccaneers NFL betting preview will give you the current odds, betting trends and picks for the Week 14 matchup, along with a stream link to watch games all season long.

Bills vs Buccaneers Week 14 NFL Betting Preview

NFL Regular Season — Week 14
Buffalo Bills (7-5, 4-2 Away) vs. Tampa Bay Buccaneers (9-3, 5-0 Home)
Date: Sunday, Dec. 12, 2021
Time: 4:25 p.m. EST
Venue: Raymond James Stadium — Tampa, FL
Coverage: Click here for the stream

Buffalo Bills Preview

Ever since picking up what many felt was a statement win over the Kansas City Chiefs back in early October, the Bills have had no semblance of consistency to their season. They have now alternated wins and losses over the last seven weeks, dropping four of seven and suddenly finding themselves in a dog fight just to hang onto a Wild Card spot in the AFC. Last Monday night saw Buffalo get manhandled by the New England Patriots on their home field. 

All of a sudden, the two glaring issues the Bills dealt with a season ago have reemerged in 2021. Buffalo cannot stop the run defensively, as was clearly illustrated in the NFL betting loss to New England. No matter how many guys crowded the box, the Patriots just kept on moving the chains on the ground. In addition, the loss of top cover corner Tre’Davious White to season-ending injury figures to leave the Bills prone in the secondary against the Buccaneers’ passing attack. Meanwhile, the Bills also cannot run the ball themselves on offense. It typically isn’t a good sign when your quarterback is also your biggest rushing threat. That is exactly the scenario that Josh Allen finds himself in again this season. 

Tampa Bay Buccaneers Preview

The reigning Super Bowl champs enter Week 14 on a three-game winning streak. After picking up another massive statistical performance against the Atlanta Falcons last week, quarterback Tom Brady is among the NFL betting favorites to win the MVP Award at age 44. He could make a strong case this Sunday against an all-too-familiar opponent from his time in Foxborough. The Bucs will once again have their top-three pass-catchers active on Sunday as tight end Rob Gronkowski was not on the team’s final injury report. Along with Mike Evans and Chris Godwin, he provides Brady with more than enough star talent to make up for the continued absence of Antonio Brown.

While Tampa Bay’s passing attack garners much of the hype and attention, it has also been clear this season that the Bucs aren’t afraid to punish defenses on the ground. Leonard Fournette has emerged as a fantasy football star this season upon taking over the bell-cow role in the backfield. He could be in line for another huge day against the poor Buffalo run defense. The Bucs’ run game will also get a boost from the return of offensive guard Ali Marpet after a one-game injury-related absence. On defense, the key for Tampa in Sunday’s NFL betting contest will be establishing a consistent pass rush. Given that the secondary is depleted by injuries, it will be paramount for the Bucs front to contain Josh Allen and prevent him from extending plays with his legs.

Credit: Mark LoMoglio/AP Photo

Bills vs Buccaneers NFL Betting Odds and Spread

NFL betting odds for Bills vs Buccaneers are taken from BetMGM Sportsbook.

Moneyline: BUF: (+150) | TB: (-175)
Spread:
BUF: +3.5 (-115) | TB: -3.5 (-105)
Total:
53.5 — Over: (-110) | Under: (-110)
Public (Spread) Betting
via Action Network: BUF: (37%) | TB: (63%)

Bills vs Buccaneers NFL Betting Trends

  • Bills are 8-3 ATS in their last 11 road games.
  • Four of the Bills’ last six games have gone under the total.
  • Buccaneers are 8-0 straight up in their last eight home games.
  • The under has hit in nine of the Buccaneers’ last ten home games when on an active winning streak of three games or more.
  • NFL betting favorites playing at home have gone 5-0 straight up and 4-1 ATS in the last five Bills vs Buccaneers head-to-head matchups.

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Bills vs Buccaneers Stats

  • Buffalo is averaging 28.0 points per game (PPG) this season (T-No. 5 in the NFL).
  • Buffalo is surrendering 16.3 PPG this season (No. 2 in the NFL).
  • Tampa Bay is averaging 31.4 PPG this season (No. 1 in the NFL).
  • Tampa Bay is surrendering 22.5 PPG this season (T-No. 16 in the NFL).

Bills vs Buccaneers Prediction

This Bills vs Buccaneers NFL betting prediction uses NumberFire’s game projections. They give Tampa Bay a 65.2% chance to win this Week 14 matchup.


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Henry’s passion for sports dates all the way back to childhood and has ultimately led to a full-fledged career as an analyst and content creator. After getting his start penning fantasy football articles, he forrayed into the betting side of the business in early 2019. His love for sports and statistics proved to be an ideal match with the dedicated research and strategy that handicapping requires. Henry currently specializes in betting analysis and picks for college football, college basketball and NASCAR. He counts the NFL, the WNBA, and NBA player props as additional leagues/markets of interest. Henry graduated from SUNY Buffalo in 2021 with a Communication Studies degree and a Psychology minor. A native of the Finger Lakes region in Upstate New York, he and his pup, Harold, have since relocated to Laramie, Wyoming. Thanks to his professional goals within the sports betting industry, there has been a whole lot of steam on the odds for a move to Las Vegas in 2023! Most of Henry’s free time is spent on outdoor adventures, playing chess, snowboarding, or reading a good book. He is also a competitive powerlifter and aspires to qualify for the USAPL Nationals meet within the next 2-3 years.

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