In a First Round NCAA Tournament game, the 6-seed Alabama Crimson Tide will face off with the 11-seed Notre Dame Fighting Irish in the West Region. Let’s take a look at the top college basketball betting odds, picks, bracketology, betting trends and KenPom Rankings, then give our Alabama vs Notre Dame prediction for the game today. 

Alabama vs Notre Dame | NCAA Tournament Bracketology

2022 NCAA Tournament
No. 6 Alabama Crimson Tide (19-13) vs. No. 11 Notre Dame Fighting Irish (23-10)
Date: Friday, March 18, 2022
Time: 4:15 PM EST
Venue: Viejas Arena — San Diego, CA
Coverage: TNT

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Alabama vs Notre Dame College Basketball Betting Picks and Odds

All college basketball betting odds for Alabama vs Notre Dame can be found at BetUS Sportsbook.

Moneyline: ALA: (-185) | ND: (+165)
Point Spread: ALA: -4 (-110) | ND: +4 (-110)
Total: 151.5 — Over: (-110) | Under: (-110)


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Credit: Gary Cosby Jr./USA TODAY Sports

KenPom Rankings | Bracketology

KenPom Rankings are from KenPom.com

TeamRkAdjOAdjDAdjT
AlabamaNo. 25116.1 (No. 15)98.7 (No. 95)71.7 (No. 11)
Notre DameNo. 51112.0 (No. 30)98.3 (No. 83)65.7 (No. 251)
  • Crimson Tide are just 1-6 ATS in their last seven NCAA Tournament games as a favorite.
  • Each of the Crimson Tide’s last five neutral site games has gone OVER the total.
  • The OVER is 4-0 in the Crimson Tide’s last four games against teams with a winning percentage above .600.
  • The OVER is 8-0-1 in the Fighting Irsh’s last nine games overall.
  • Each of the Fighting Irish’s last five games following an ATS win has gone OVER the total.
  • The OVER is 4-0 in the Fighting Irish’s last four games against teams with a winning record.

Alabama vs Notre Dame Prediction | March Madness Picks and Bracketology

Notre Dame has to survive a double-overtime thriller against Rutgers in the First Four just to reach the main NCAA Tournament bracket. Mike Brey deserves a ton of credit for getting the most out of a marginal Fighting Irish team in terms of pure talent. Speaking of talent, Alabama quite clearly has the advantage on this front.

The Crimson Tide are led by a pair of junior guards in Jaden Shackelford and Jahvon Quinerly. The team’s lack of size has led Nate Oats to utilize a four-guard lineup for the majority of games. As a result, Alabama loves to run and gun. The Tide average the 11th-fastest adjusted tempo in the nation according to KenPom. They also averaged the sixth-most three-point field goal attempts on a per-game basis. Although Alabama is not a team to shy away from shooting the long ball, the Tide only managed to hit on 30.5% of attempted three-pointers as a team.

While an overreliance on the three-ball might not be appealing for college basketball picks, the Tide also will have advantages in speed and athleticism in this matchup with Notre Dame. If the Irish defense looks anything like it did in the First Four marathon against Rutgers, Alabama should be able to achieve success driving to the rim as well. Look for the Crimson Tide’s superior talent to win out in this one.

Our college basketball betting Alabama vs Notre Dame prediction tonight will be Alabama -4 at BetUS

For what it’s worth, the ESPN Matchup Predictor gives Alabama a 64.3% chance to win.


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Henry’s passion for sports dates all the way back to childhood and has ultimately led to a full-fledged career as an analyst and content creator. After getting his start penning fantasy football articles, he forrayed into the betting side of the business in early 2019. His love for sports and statistics proved to be an ideal match with the dedicated research and strategy that handicapping requires. Henry currently specializes in betting analysis and picks for college football, college basketball and NASCAR. He counts the NFL, the WNBA, and NBA player props as additional leagues/markets of interest. Henry graduated from SUNY Buffalo in 2021 with a Communication Studies degree and a Psychology minor. A native of the Finger Lakes region in Upstate New York, he and his pup, Harold, have since relocated to Laramie, Wyoming. Thanks to his professional goals within the sports betting industry, there has been a whole lot of steam on the odds for a move to Las Vegas in 2023! Most of Henry’s free time is spent on outdoor adventures, playing chess, snowboarding, or reading a good book. He is also a competitive powerlifter and aspires to qualify for the USAPL Nationals meet within the next 2-3 years.

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